| 产品编号 | bsm-61171R |
| 英文名称 | PTPN6 Recombinant Rabbit mAb |
| 中文名称 | 蛋白酪氨酸磷酸酶1C重组兔单抗 |
| 别 名 | 70Z-SHP; EC 3.1.3.48; HCP; HCPH; PTN6; PTP-1C; PTP1C; PTPN6; SH-PTP1; SHP1. |
| 抗体来源 | Rabbit |
| 克隆类型 | |
| 克 隆 号 | |
| 产品应用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 68 kDa |
| 检测分子量 | 68 |
| 性 状 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human SHP1: 520-595 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis. SWISS: P29350 Gene ID: 5777 蛋白酪氨酸磷酸酶1(SHP-1)能是一个潜在的抑癌基因，它负性调节c-kit基因而抑制肿瘤的发生; SHP-1为含SH2域(src homology-2 domain)的酪氨酸磷酸酶-1，主要表达于造血细胞，因此又称为造血细胞磷酸酶（hematopoietic cell phosphatase，HCP，也称为SHP-1或SHPTP1）。 |
| 产品图片 |
25 ug total protein per lane of various lysates (see on figure) probed with PTPN6 monoclonal antibody, unconjugated (bsm-61171R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
