| 产品编号 | bsm-61221R |
| 英文名称 | CCR3 Recombinant Rabbit mAb |
| 中文名称 | 细胞表面趋化因子受体3重组兔单抗 |
| 别 名 | CCR3; CD193; CCCKR3; CMKBR3; CKR3; CMKBR1L2; C-C chemokine receptor type 3. |
| 抗体来源 | Rabbit |
| 克隆类型 | |
| 克 隆 号 | 12F9 |
| 产品应用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 41 kDa |
| 检测分子量 | 60 |
| 性 状 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human CCR3: 300-355 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection. SWISS: P51677 Gene ID: 1232 趋化因子受体3(CCR3)主要在嗜酸粒细胞，Th2淋巴细胞，肥大细胞，支气管上皮细胞上表达， CCR3介导嗜酸粒细胞内有丝分裂原活化蛋白激酶（MAPK） 细胞外信号调节激酶-2（ERK2）、p38和JNK的活化。 |
| 产品图片 |
25 ug total protein per lane of various lysates (see on figure) probed with CCR3 monoclonal antibody, unconjugated (bsm-61221R) at 1:500 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
