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RabbitAnti-INPP4B Recombinant Rabbit mAb  antibody (bsm-61303R)
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说明书: 50ul  100ul  
25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包装/询价

产品编号 bsm-61303R
英文名称 INPP4B Recombinant Rabbit mAb
中文名称 聚磷酸肌醇磷酸酶4B重组兔单抗
别    名 4-bisphosphate 4-phosphatase; Inositol polyphosphate 4 phosphatase type II 105kDa; Inositol polyphosphate 4-phosphatase type II; Inpp4b; MGC132014; Type II inositol 3, 4 bisphosphate 4 phosphatase; Type II inositol-3.  
抗体来源 Rabbit
克隆类型
克 隆 号
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 105 kDa
检测分子量 107
性    状 Liquid
免 疫 原 A synthesized peptide derived from human INPP4B: 1-54/924 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
保存条件 Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 3,4-trisphosphate. Plays a role in the late stages of macropinocytosis by dephosphorylating phosphatidylinositol 3,4-bisphosphate in membrane ruffles.The lipid phosphatase activity is critical for tumor suppressor function. Antagonizes the PI3K-AKT/PKB signaling pathway by dephosphorylating phosphoinositides and thereby modulating cell cycle progression and cell survival

SWISS:
O15327

Gene ID:
8821

产品图片
25 ug total protein per lane of various lysates (see on figure) probed with INPP4B monoclonal antibody, unconjugated (bsm-61303R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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