| 产品编号 | bsm-61495R |
| 英文名称 | PCSK9 Recombinant Rabbit mAb |
| 中文名称 | 神经细胞凋亡调节转化蛋白1/前蛋白转化酶枯草溶菌素9重组兔单抗 |
| 别 名 | HCHOLA3; LDLCQ1; NARC1; Neural apoptosis regulated convertase 1; PC9; PCSK9; Proprotein convertase 9. |
| 抗体来源 | Rabbit |
| 克隆类型 | |
| 克 隆 号 | 19A8 |
| 产品应用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 74 kDa |
| 检测分子量 | 62,78 |
| 性 状 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human PCSK9: 550-600/692 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. SWISS: Q8NBP7 Gene ID: 255738 前蛋白转化酶枯草溶菌素9(PCSK9)是近年来新发现的一种与调节脂质代谢密切相关的基因,编码前蛋白转化酶NARC-1。Narc-1/pcsk9可通过调节细胞表面的低密度脂蛋白受体(LDLR)水平,参与脂质代谢,从而在动脉粥样硬化性疾病的发生、发展中发挥重要作用。 |
| 产品图片 |
25 ug total protein per lane of various lysates (see on figure) probed with PCSK9 monoclonal antibody, unconjugated (bsm-61495R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
|
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
