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RabbitAnti-TRADD Recombinant Rabbit mAb  antibody (bsm-61653R)
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说明书: 50ul  100ul  
25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包装/询价

产品编号 bsm-61653R
英文名称 TRADD Recombinant Rabbit mAb
中文名称 肿瘤坏死因子受体1相关死亡域蛋白重组兔单抗
别    名 AA930854; TNFR1 associated DEATH domain protein; tradd.  
抗体来源 Rabbit
克隆类型
克 隆 号 2C10
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 34 kDa
检测分子量 34
性    状 Liquid
免 疫 原 A synthesized peptide derived from human TRADD: 210-312 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
保存条件 Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD.Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.

SWISS:
Q15628

Gene ID:
8717

TRADD在凋亡信号传导中起重要作用,近年来多用于研究其在肿瘤中的作用,探讨TRADD在促细胞凋亡和促细胞存活的机制如何控制,将有利于我们了解肿瘤发病机理。
产品图片
25 ug total protein per lane of various lysates (see on figure) probed with TRADD monoclonal antibody, unconjugated (bsm-61653R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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