| 产品编号 | bsm-61720R |
| 英文名称 | IKK epsilon Recombinant Rabbit mAb |
| 中文名称 | 核因子κB抑制蛋白E重组兔单抗 |
| 别 名 | IKBKE; IKK-E; IKK-i; IKKE; IKKI; IKKi/IKKe. |
| 抗体来源 | Rabbit |
| 克隆类型 | |
| 克 隆 号 | |
| 产品应用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 80 kDa |
| 检测分子量 | 80 |
| 性 状 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human IKK epsilon: 32-65 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. May play a special role in the immune response. Protects cells against DNA damage-induced cell death. SWISS: Q14164 Gene ID: 9641 I kappa B kinase epsilon(IKKe)也是丝氨酸/苏氨酸蛋白激酶家族.可以磷酸化IkB，从而激活NF-kB通路，促进NF-kB核移位,并最终降解NF-kB的抑制剂. IKKe可表达在很多组织细胞中;胸腺、胰腺、脾、胎盘、外周血白细胞，也可少量表达在肺、肾、前列腺癌、卵巢、结肠。但最多表达在乳腺肿瘤上，IKBKE在人类乳腺癌中明显高表达，这种新的乳腺癌易感基因在肿瘤的形成和发展中起着及其关键的作用。IKBKE蛋白不同于乳腺癌易感基因BRCA1和BRCA2，是先天具有的。带有这些遗传变异 |
| 产品图片 |
Western blot analysis of Raji cell lysate. Using IKK epsilon (bsm-61720R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
|
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
