| 产品编号 | bsm-61737R |
| 英文名称 | SAMHD1/MOP5 Recombinant Rabbit mAb |
| 中文名称 | 单核细胞蛋白5重组兔单抗 |
| 别 名 | CHBL2; DCIP; HDDC1; MOP-5; SBBI88; hSAMHD1; E330031J07Rik; Mg11; mSAMHD1; SAMH1_HUMAN; SAMHD1; dNTPase; Dendritic cell-derived IFNG-induced protein (DCIP); Monocyte protein 5 (MOP-5); SAM domain and HD domain-containing protein 1 (hSAMHD1); 3.1.5.-; MOP5; SAMH1_MOUSE; Interferon-gamma-inducible protein Mg11; SAM domain and HD domain-containing protein 1 (mSAMHD1); Mg21; SAMH1_DANRE; |
| 抗体来源 | Rabbit |
| 克隆类型 | |
| 克 隆 号 | 3G4 |
| 产品应用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 72 kDa |
| 检测分子量 | 72 |
| 性 状 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human SAMHD1: 580-626/626 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Protein that acts both as a host restriction factor involved in defense response to virus and as a regulator of DNA end resection at stalled replication forks.Has deoxynucleoside triphosphate (dNTPase) activity, which is required to restrict infection by viruses, such as HIV-1: dNTPase activity reduces cellular dNTP levels to levels too low for retroviral reverse transcription to occur, blocking early-stage virus replication in dendritic and other myeloid cells . SWISS: Q9Y3Z3 Gene ID: 25939 近来经科学家研究发现，SAMHD1蛋白有抑制骨髓细胞感染HIV（艾滋病病毒）的机制，SAMHD1蛋白能感应到诸如巨噬细胞和树状细胞等骨髓细胞感染到HIV-1病毒（HIV分为1型和2型，1型是目前全球流行的主要毒株，2型目前只在西非流行）和其他相关的免疫缺陷病毒，并阻止病毒副本在这些细胞内的合成，从而抑制HIV病毒感染。 |
| 产品图片 |
Western blot analysis of MCF7 cell lysate. Using SAMHD1/MOP5 (bsm-61737R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
