| 产品编号 | bsm-61774R |
| 英文名称 | Presenilin 1 Recombinant Rabbit mAb |
| 中文名称 | 早老素蛋白1重组兔单抗 |
| 别 名 | AD3; Ad3h; FAD; Protein S182; PS1-CTF12; PSEN1; PSNL1; S182. |
| 抗体来源 | Rabbit |
| 克隆类型 | |
| 克 隆 号 | 8A20 |
| 产品应用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 53 kDa |
| 检测分子量 | 28 |
| 性 状 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human Presenilin 1: 25-78/467 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Requires the presence of the other members of the gamma-secretase complex for protease activity.Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels. SWISS: P49768 Gene ID: 5663 此抗体识别分子量为45-50 kDa早老素蛋白-1。PS-1主要在神经细胞中表达，该蛋白集中于体细胞和树突状细胞中。相反，再早发家族AD（FAD）中和散发AD病人中，PS1免疫反应出现在老年斑和神经纤维缠结的神经炎中，树突状细胞中表达。 |
| 产品图片 |
Western blot analysis of Jurkat cell lysate. Using Presenilin 1 (bsm-61774R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
Paraformaldehyde-fixed, paraffin embedded Human Glioma; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Presenilin 1 Monoclonal Antibody, Unconjugated(bsm-61774R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Presenilin 1 Monoclonal Antibody, Unconjugated(bsm-61774R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Rat Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Presenilin 1 Monoclonal Antibody, Unconjugated(bsm-61774R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Mouse Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Presenilin 1 Monoclonal Antibody, Unconjugated(bsm-61774R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
