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RabbitAnti-RING2 Recombinant Rabbit mAb  antibody (bsm-61821R)
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说明书: 50ul  100ul  
25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包装/询价

产品编号 bsm-61821R
英文名称 RING2 Recombinant Rabbit mAb
中文名称 环指蛋白2重组兔单抗
别    名 BAP1; DING; BAP-1; HIPI3; RING2; RING1B.  
抗体来源 Rabbit
克隆类型
克 隆 号
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 38 kDa
检测分子量 38
性    状 Liquid
免 疫 原 A synthesized peptide derived from human RING2: 100-160/336 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
保存条件 Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Acts as the main E3 ubiquitin ligase on histone H2A of the PRC1 complex, while RING1 may rather act as a modulator of RNF2/RING2 activity (Probable). Association with the chromosomal DNA is cell-cycle dependent. In resting B- and T-lymphocytes, interaction with AURKB leads to block its activity, thereby maintaining transcription in resting lymphocytes.Also acts as a negative regulator of autophagy by mediating ubiquitination of AMBRA1, leading to its subsequent degradation.

SWISS:
Q99496

Gene ID:
6045

产品图片
Western blot analysis of HeLa cell lysate. Using RING2 (bsm-61821R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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