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RabbitAnti-IL-23 Recombinant Rabbit mAb  antibody (bsm-61831R)
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说明书: 50ul  100ul  
25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包装/询价

产品编号 bsm-61831R
英文名称 IL-23 Recombinant Rabbit mAb
中文名称 白介素-23重组兔单抗
别    名 IL 23A; IL 23p19; IL12B; IL23; Il23a; IL23P19; P19; SGRF.  
抗体来源 Rabbit
克隆类型
克 隆 号 15E15
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 21 kDa
检测分子量 21
性    状 Liquid
免 疫 原 A synthesized peptide derived from human IL 23A: 118-189 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
保存条件 Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Associates with IL12B to form the pro-inflammatory cytokine IL-23 that plays different roles in innate and adaptive immunity.Released by antigen-presenting cells such as dendritic cells or macrophages, binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R to activate JAK2 and TYK2 which then phosphorylate the receptor to form a docking site leading to the phosphorylation of STAT3 and STAT4.

SWISS:
Q9NPF7

Gene ID:
51561

IL23(Interleukin-23)作为一种前炎症细胞因子,具有影响机体免疫反应和抗感染作用,白介素23能连接肿瘤关联的炎症和肿瘤免疫监督缺乏关系的细胞因子。存在于很多人类肿瘤中,能通过促进血管形成来帮助肿瘤生长。
产品图片
293T (H) cells were treated with or without LPS and IFN (40ng/mL) for 24 h, BFA (300ng/mL) for 24 h, 25 μg total protein per lane of cell lysates (see on figure) probed with IL-23 polyclonal antibody, unconjugated (bsm-61831R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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