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RabbitAnti-TSC1 Recombinant Rabbit mAb  antibody (bsm-62173R)
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说明书: 50ul  100ul  
25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包装/询价

产品编号 bsm-62173R
英文名称 TSC1 Recombinant Rabbit mAb
中文名称 结节性硬化症蛋白1重组兔单抗
别    名 Hamartin; kiaa0243; LAM; TSC; Tsc1; Tuberous sclerosis 1.  
抗体来源 Rabbit
克隆类型
克 隆 号
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 130 kDa
检测分子量 150
性    状 Liquid
免 疫 原 A synthesized peptide derived from human Hamartin: 1100-1164/1164 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
保存条件 Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Non-catalytic component of the TSC-TBC complex, a multiprotein complex that acts as a negative regulator of the canonical mTORC1 complex, an evolutionarily conserved central nutrient sensor that stimulates anabolic reactions and macromolecule biosynthesis to promote cellular biomass generation and growth.

SWISS:
Q92574

Gene ID:
7248

    结节性硬化症为常染色体显性遗传,也常见散发病例。是肿瘤抑制基因,基因产物分别为Hamartin和tuberin,两者均调节细胞生长。     结节性硬化症(tuberous sclerosis)又称结节性脑硬化,Bourneville病。本病可归类于神经皮肤综合征(亦称斑痣性错构瘤病),是源于外胚层的器官发育异常所致,病变累及神经系统、皮肤和眼,也可累及中胚层,内胚层器官如心、肺、骨,肾和胃肠等。皮脂腺瘤是皮肤神经末梢、增生的结缔组织和血管组成,视网膜可见胶质瘤、神经节细胞瘤,心、肾、肺、
产品图片
25 ug total protein per lane of various lysates (see on figure) probed with TSC1 monoclonal antibody, unconjugated (bsm-62173R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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