产品编号 | bsm-62173R |
英文名称 | TSC1 Recombinant Rabbit mAb |
中文名称 | 结节性硬化症蛋白1重组兔单抗 |
别 名 | Hamartin; kiaa0243; LAM; TSC; Tsc1; Tuberous sclerosis 1. |
抗体来源 | Rabbit |
克隆类型 | |
克 隆 号 | |
产品应用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 130 kDa |
检测分子量 | 150 |
性 状 | Liquid |
免 疫 原 | A synthesized peptide derived from human Hamartin: 1100-1164/1164 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
Non-catalytic component of the TSC-TBC complex, a multiprotein complex that acts as a negative regulator of the canonical mTORC1 complex, an evolutionarily conserved central nutrient sensor that stimulates anabolic reactions and macromolecule biosynthesis to promote cellular biomass generation and growth. SWISS: Q92574 Gene ID: 7248 结节性硬化症为常染色体显性遗传,也常见散发病例。是肿瘤抑制基因,基因产物分别为Hamartin和tuberin,两者均调节细胞生长。 结节性硬化症(tuberous sclerosis)又称结节性脑硬化,Bourneville病。本病可归类于神经皮肤综合征(亦称斑痣性错构瘤病),是源于外胚层的器官发育异常所致,病变累及神经系统、皮肤和眼,也可累及中胚层,内胚层器官如心、肺、骨,肾和胃肠等。皮脂腺瘤是皮肤神经末梢、增生的结缔组织和血管组成,视网膜可见胶质瘤、神经节细胞瘤,心、肾、肺、 |
产品图片 | |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |