产品编号 | bsm-63018R |
英文名称 | Phospho-VASP (Ser156) Recombinant Rabbit mAb |
中文名称 | 磷酸化血管扩张刺激磷蛋白重组兔单抗 |
别 名 | Vasodilator stimulated phosphoprotein; VASP. |
抗体来源 | Rabbit |
克隆类型 | |
克 隆 号 | |
产品应用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 40 kDa |
检测分子量 | 46 |
性 状 | Liquid |
免 疫 原 | A synthesized peptide derived from human VASP around the phosphorylation site of S156: RRV-pS-NAG |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. SWISS: P50552 Gene ID: 7408 VASP属于Ena-VASP蛋白家族,是一种肌动蛋白结合蛋白。细胞骨架动力学的调节在细胞粘附、细胞变形、细胞移动等生理过程中是必需的。VASP可能也参与细胞内信号通道,该通道调节整联蛋白与细胞外基质间的相互作用。VASP被周期核苷酸依赖型激酶PKA与PKG所调节,在一些肿瘤的分化、增值、转移中起到一定的作用,在肿瘤中有较高的表达。 近年来的研究发现VASP在与细胞骨架调节有关的各种细胞行为中起着重要作用,如神经细胞轴索的延伸、T细胞的移动、成纤维细胞的迁移等。 VAS |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |