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RabbitAnti-CXorf36 Rabbit pAb  antibody (bs-0488R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-0488R
英文名称 CXorf36 Rabbit pAb
中文名称 脱羧酶蛋白体36抗体
别    名 4930578C19Rik; CXorf36; DIA1R; EPQL1862; PRO3743; bA435K1.1; DIK2B_HUMAN; DIPK2B; Deleted in autism-related protein 1;   
研究领域 肿瘤  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Human,  (predicted: Mouse, Rat, Dog, Cow, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 20/45 kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CXorf36: 91-182/182 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number of conditions related to an unsual number and combination of sex chromosomes being inherited. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome. The CXorf36 gene product has been provisionally designated CXorf36 pending further characterization.

Subcellular Location:
Secreted (Potential).

DISEASE:
Note=Genetic variations in CXorf36 may be associated with susceptibility to autism.

Similarity:
Belongs to the DIA1 family.

SWISS:
Q9H7Y0

Gene ID:
79742

Database links:

Entrez Gene: 79742 Human

SwissProt: Q9H7Y0 Human

Unigene: 98321 Human



经研究:CXorf36蛋白是通过其水解酶活性,在肿瘤的发生、生长或侵袭过程中发挥重要作用。对关于CXorf36基因功能的研究,其在肿瘤组织中的定位、对细胞生物学功能的影响需进一步研究。

文献参考: 肾癌相关基因CXorf36的克隆及亚定位研究
产品图片
Tissue/cell: human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-CXorf36 Polyclonal Antibody, Unconjugated(bs-0488R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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