| 产品编号 | bs-1250R |
| 英文名称 | Gax Rabbit pAb |
| 中文名称 | 生长终止特异性同源盒基因抗体 |
| 别 名 | growth arrest-specific homeobox; Homeobox protein MOX-2; Mesenchyme homeobox 2; mesenchyme homeobox 2-like; Growth arrest-specific homeobox; GAX; growth arrest homeobox transcription factor GAX; mesenchyme homeobox 2; MEOX2_HUMAN. |
| 研究领域 | 肿瘤 心血管 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 33 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞核 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Gax: 201-304/304 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimers disease. Function: Role in mesoderm induction and its earliest regional specification, somitogenesis, and myogenic and sclerotomal differentiation. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle (By similarity). Subunit: Interacts with RNF10. Subcellular Location: Nucleus. Nucleus speckle. Similarity: Contains 1 homeobox DNA-binding domain. SWISS: P50222 Gene ID: 4223 Database links: Entrez Gene: 4223 Human Entrez Gene: 17286 Mouse Omim: 600535 Human SwissProt: P50222 Human SwissProt: P32443 Mouse Unigene: 170355 Human Unigene: 341398 Mouse Unigene: 34890 Rat Gax主要在血管平滑肌细胞和内皮细胞中表达的同源异形盒基因,但Gax基因过表达可以抑制血管平滑肌细胞和内皮细胞的增殖，Gax也是脊椎动物肢体发育的重要调节因子，目前除用于心血管方面的研究，也用于肿瘤血管方面的探索。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
