| 产品编号 | bs-0716R |
| 英文名称 | CIDEB Rabbit pAb |
| 中文名称 | 细胞死亡激活剂CIDE-B抗体 |
| 别 名 | cell death activator CIDE-B; Cell death activator CIDE B; Cell death inducing DFFA like effector B; CIDEB_HUMAN; cell death-inducing DFFA-like effector B; Cide-b. |
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Specific References (1) | bs-0716R has been referenced in 1 publications.
111
[IF=2.742] Liu, Yanrong. et al. Cinnamaldehyde affects lipid droplets metabolism after adipogenic differentiation of C2C12 cells. MOL BIOL REP. 2022 Dec;:1-7 WB ; Mouse. 222
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| 研究领域 | 肿瘤 细胞生物 染色质和核信号 细胞凋亡 细胞周期蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | Human, Mouse, Rat, (predicted: Dog, Pig, Cow, Horse, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 24 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CIDEB: 118-219/219 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as an inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE A and CIDE B were recently identified. CIDE contains a new type of domain termed CIDE N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE B induces apoptosis, which is inhibited by DFF45. CIDE B is a DFF45 inhibitable effector that promotes cell death and DNA fragmentation. CIDE B is expressed mainly in liver and small intestine and at lower levels in spleen, colon, kidney, peripheral blood lymphocytes, and bone marrow. Function: Activates apoptosis. Subunit: Inhibited by DFFB. Interacts with DFFA and DFFB. Tissue Specificity: Highly expressed in liver and small intestine and, at lower levels, in colon, kidney and spleen. Similarity: Contains 1 CIDE-N domain. SWISS: Q9UHD4 Gene ID: 27141 Database links: Entrez Gene: 27141 Human Entrez Gene: 12684 Mouse Omim: 604441 Human SwissProt: Q546V8 Human SwissProt: Q9UHD4 Human SwissProt: O70303 Mouse Unigene: 642693 Human Unigene: 696081 Human Unigene: 708040 Human Unigene: 466766 Mouse Unigene: 204016 Rat CIDEB是在细胞凋亡的过程中诱导分泌的一种蛋白，在棕色脂肪组织，肝脏和肾脏中发现有高水平的DFF45-like effector--DFF45样效应子b蛋白，简称cideb。CIDEB具有调控脂质代谢的作用。 |
| 产品图片 |
Sample:
Large intestine (Mouse) Lysate at 40 ug
Raw264.7(Mouse) Cell Lysate at 30 ug
Primary: Anti- CIDEB (bs-0716R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 24 kD
Observed band size: 27 kD
Sample:
Lane 1: Rat Small intestine tissue lysates
Lane 2: Human HL-60 cell lysates
Primary: Anti-CIDEB (bs-0716R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 24 kDa
Observed band size: 27 kDa
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
