| 产品编号 |
bs-1554R |
| 英文名称 |
Aquaporin 5 Rabbit pAb |
| 中文名称 |
水通道蛋白5抗体 |
| 别 名 |
Aquaporin 5; AQP5; AQP 5; AQP-5; AQP5_HUMAN; Aquaporin-5. |
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Specific References (10) | bs-1554R has been referenced in 10 publications.
111
[IF=5.23] Yi, TacGhee, et al. "Single Cell Clones Purified from Human Parotid Glands Display Features of Multipotent Epitheliomesenchymal Stem Cells." Scientific Reports 6 (2016). FCM ; Human. 222
111
[IF=4.25] Lim, Jae-Yol, et al. "Establishment and Characterization of Mesenchymal Stem Cell-like Clonal Stem Cells from Mouse Salivary Glands." Tissue Engineering (2014). Mouse. 222
111
[IF=3.419] Shota Mitsuboshi. et al. A novel alveolar epithelial cell sheet fabricated under feeder-free conditions for potential use in pulmonary regenerative therapy. Regen Ther. 2022 Mar;19:113 IHC ; Rat. 222
111
[IF=2.826] Takanori Watanabe et al. Aquaporin 3 Expression in Endometrioid Carcinoma of the Uterine Body Correlated With Early Stage and Lower Grade. Pathol Oncol Res. 2020 Oct;26(4):2247-2253. IHC ; Human. 222
111
[IF=2.634] Liu X. et al. Effects of Different Ligands in the Notch Signaling Pathway on the Proliferation and Transdifferentiation of Primary Type II Alveolar Epithelial Cells.. Front Pediatr. 2020 Aug;8:452-452 WB ; Rat. 222
111
[IF=2.311] Haifa Alkhalifa. et al. Inhibition of aquaporins as a potential adjunct to breast cancer cryotherapy. Oncol Lett. 2021 Jun;21(6):1-11 WB ; Human. 222
111
[IF=2.041] Wang D et al. Suppression of high-mobility group box 1 ameliorates xerostomia in a sjogren syndrome-triggered mouse model. Can J Physiol Pharmacol. 2020 Jan 14. WB ; Mouse. 222
111
[IF=1.935] Sato K et al. Different Prognostic Implications of Aquaporin-1 and Aquaporin-5 Expression among Different Histological Types of Ovarian Carcinoma.Pathol Oncol Res. 2018 Jul 19. IHC-P ; Human. 222
111
[IF=1.248] Wei W et al. Estradiol Induced Estrogen Receptor-mediated Transcription and Expression of Aquaporin5.Chemical Research in Chinese Universities,2019 35(2), 239–244. WB,ICF&IHC-P ; Mouse&Human. 222
111
[IF=1.09] Wang, Wei, et al. "Expression of AQP5 and AQP8 in human colorectal carcinoma and their clinical significance." World journal of surgical oncology 10.1 (2012): 1-5. IHC-P ; Human. 222
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| 研究领域 |
信号转导 通道蛋白 上皮细胞 |
| 抗体来源 |
Rabbit |
| 克隆类型 |
Polyclonal |
| 克 隆 号 |
|
| 交叉反应 |
Human, Mouse, Rat,
(predicted: Dog, Pig, Cow, Horse, Sheep, )
|
| 产品应用 |
WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 |
29 kDa |
| 检测分子量 |
|
| 细胞定位 |
细胞膜
|
| 性 状 |
Liquid |
| 浓 度 |
1mg/ml |
| 免 疫 原 |
KLH conjugated synthetic peptide derived from mouse AQP5: 201-265/265 <Cytoplasmic> |
| 亚 型 |
IgG |
| 纯化方法 |
affinity purified by Protein A |
| 缓 冲 液 |
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 |
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed |
PubMed |
| 产品介绍 |
Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13. [provided by RefSeq, Jul 2008]
Function: Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions.
Subcellular Location: Membrane; Multi-pass membrane protein.
Similarity: Belongs to the MIP/aquaporin (TC 1.A.8) family.
SWISS: Q9WTY4
Gene ID: 11830
Database links:
Entrez Gene: 362 Human
Entrez Gene: 11830 Mouse
Entrez Gene: 25241 Rat
Omim: 600442 Human
SwissProt: P55064 Human
SwissProt: Q9WTY4 Mouse
SwissProt: P47864 Rat
Unigene: 298023 Human
Unigene: 45580 Mouse
Unigene: 10066 Rat
水通道蛋白(Aquaporin,AQP)是一组与水分子通透有关的特异性细胞膜转运蛋白。其中,AQP 5在哺乳动物气管、支气管的上皮细胞表达较常见.
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| 产品图片 |
Sample:
Lane 1: Mouse Lung tissue lysates
Lane 2: Rat Stomach tissue lysates
Primary: Anti-Aquaporin 5 (bs-1554R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 29 kD
Observed band size: 27 kD
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