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RabbitAnti-Connexin-36 Rabbit pAb  antibody (bs-1266R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-1266R
英文名称 Connexin-36 Rabbit pAb
中文名称 间隙连接蛋白36抗体
别    名 Connexin 36; CX36; Gap junction protein alpha 9; gap junction protein, alpha 9, 36kDa; GJA9; MGC138315; MGC138319; CXD2_HUMAN.  
研究领域 神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 36 kDa
检测分子量
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Connexin-36: 201-321/321 <Cytoplasmic>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a member of the connexin protein family. Connexins are gap junction proteins which are arranged in groups of 6 around a central pore to form a connexon, a component of the gap junction intercellular channel. The channels formed by this protein allow cationic molecule exchange between human beta cells and may function in the regulation of insulin secretion. [provided by RefSeq, Oct 2012]

Function:
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

Subunit:
A connexon is composed of a hexamer of connexins.

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

Tissue Specificity:
Highly expressed in neurons.

Similarity:
Highly expressed in neurons.
Belongs to the connexin family. Delta-type subfamily.

SWISS:
Q9UKL4

Gene ID:
57369

Database links:

Entrez Gene: 395273 Chicken

Entrez Gene: 282577 Cow

Entrez Gene: 57369 Human

Entrez Gene: 14617 Mouse

Entrez Gene: 50564 Rat

Entrez Gene: 378444 Zebrafish

Omim: 607058 Human

SwissProt: Q866T7 Cow

SwissProt: Q9UKL4 Human

SwissProt: O54851 Mouse

SwissProt: Q6PDP3 Mouse

SwissProt: O70610 Rat

Unigene: 283816 Human

Unigene: 389394 Mouse

Unigene: 9904 Rat



间隙连接是神经系统构成电突触的结构基础,参与调控神经冲动纤毫传递和复杂神经网络的整合,而Cx36是唯一一个在神经系统中优先表达的Cx,因此成为电生理研究主要蛋白。
产品图片
Sample: Lane 1: Human MCF-7 cell lysates Lane 2: Human Jurkat cell lysates Primary: Anti-Connexin-36 (bs-1266R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 36 kDa Observed band size: 35 kDa
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