| 产品编号 | bs-1422R |
| 英文名称 | MRP4/ABCC4 Rabbit pAb |
| 中文名称 | 多药耐药相关蛋白4抗体 |
| 别 名 | MOAT-B; MOATB; MRP4; ABCC4-N1; D630049P08Rik; MRP4_HUMAN; ABCC4; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B (MOAT-B); Multidrug resistance-associated protein 4; 7.6.2.-; 7.6.2.2; 7.6.2.3; ATP binding cassette subfamily C member 4 (PEL blood group); ATP-binding cassette, sub-family C (CFTR/MRP), member 4; ATP binding cassette subfamily C member 4; canalicular multispecific organic anion transporter (ABC superfamily); bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4); multispecific organic anion transporter B |
| 研究领域 | 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Guinea Pig, ) |
| 产品应用 | ELISA=1:5000-10000 IHC-P=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 149kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MRP4: 751-880/1325 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. [provided by RefSeq, Jul 2008]. Function: May be an organic anion pump relevant to cellular detoxification. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Widely expressed, with particularly high levels in prostate, but is barely detectable in liver. Similarity: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. Contains 2 ABC transmembrane type-1 domains. Contains 2 ABC transporter domains. SWISS: O15439 Gene ID: 10257 Database links: Entrez Gene: 10257 Human Entrez Gene: 239273 Mouse Omim: 605250 Human SwissProt: O15439 Human Unigene: 508423 Human Unigene: 40537 Mouse |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
