| 产品编号 | bs-1666R |
| 英文名称 | CCL21 Rabbit pAb |
| 中文名称 | 淋巴细胞趋化因子CCL21/Exodus 2抗体 |
| 别 名 | 6Ckine; beta chemokine exodus 2; beta chemokine exodus2; CCL 21; CCL21; Chemokine C C motif ligand 21; Chemokine CC motif ligand 21; CKb 9; CKb9; ECL; Efficient Chemoattractant for Lymphocytes; Exodus 2; Exodus2; Exodus-2; SCYA 21; SCYA21; Secondary lymphoid tissue chemokine; SLC; Small inducible cytokine A21; Small inducible cytokine subfamily A(Cys Cys) member 21; Small inducible cytokine subfamily A(Cys-Cys) member 21; Small inducible cytokine subfamily A member 21; TCA 4; TCA4. |
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Specific References (6) | bs-1666R has been referenced in 6 publications.
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[IF=17.521] Jiabin Xu. et al. CCR7 Mediated Mimetic Dendritic Cell Vaccine Homing in Lymph Node for Head and Neck Squamous Cell Carcinoma Therapy. Advanced Science. 2023 Apr;:2207017 IF ; Mouse. 222
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[IF=6.354] Hao, Yanan. et al. Gut microbiota-testis axis: FMT improves systemic and testicular micro-environment to increase semen quality in type 1 diabetes. MOL MED. 2022 Dec;28(1):1-17 IF ; Mouse. 222
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[IF=5.029] Hanhan Fang. et al. Gut-Spleen Axis: Microbiota via Vascular and Immune Pathways Improve Busulfan-Induced Spleen Disruption | mSphere. MSPHERE. 2022 Dec;: IF ; Mouse. 222
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[IF=2.52] Expression of Pref-1 and Related Chemokines during theDevelopment of Rat Mesenteric Lymph Nodes.(2018)Biomed Environ Sci.ul;31(7):507-514. IHC ; Rat. 222
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[IF=2.23] Borrelli, G. M., et al. "Immunohistochemical Investigation of Metastasis-Related Chemokines in Deep-Infiltrating Endometriosis and Compromised Pelvic Sentinel Lymph Nodes." Reproductive Sciences (2015): 1933719115592711. IHC-P ; Human. 222
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[IF=0] Borrelli, Giuliano. D6926. Diss. Freie Universität Berlin, 2015. IHC-P ; Human. 222
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| 研究领域 | 肿瘤 细胞生物 免疫学 转录调节因子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 15 kDa |
| 检测分子量 | |
| 细胞定位 | 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CCL21: 24-134/134 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq, Jul 2008]. Function: Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Potent mesangial cell chemoattractant. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Subcellular Location: Secreted. Tissue Specificity: Expressed strongly in lung, spleen, thymus, peripheral and mesentric lymph nodes. Also expressed in the testis, kidney, liver, and heart. DISEASE: Note=Mice carrying an autosomal recessive mutation designated paucity of lymph node T-cells (plt) show dramatically reduced numbers of T-cells in lymph nodes, Peyer patches, and the white pulp of the spleen. Plt seems to correspond to Scya21b. Similarity: Belongs to the intercrine beta (chemokine CC) family. SWISS: O00585 Gene ID: 6366 Database links: Entrez Gene: 6366 Human Omim: 602737 Human SwissProt: O00585 Human |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
