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RabbitAnti-CCR2 + CCR5 Rabbit pAb  antibody (bs-1671R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-1671R
英文名称 CCR2 + CCR5 Rabbit pAb
中文名称 细胞表面趋化因子受体2A抗体
别    名 CC-CKR-2; C-C Chemokine receptor 2A; C C CKR 2; CC chemokine receptor type 2; CC CKR 2; CCCKR2; CCR 2; CCR1L; CCR2A; CCR2B; CCR5L; CD192; CD192 antigen; Chemokine C C motif receptor 2; Chemokine CC Motif Receptor 2; CKR 2; CKR2; CKR2A; CKR2B; CMKBR2; MCP 1 R; MCP1 RECEPTOR; MCP1R; Monocyte chemoattractant protein 1 receptor; Monocyte Chemotactic Protein 1 Receptor; FLJ78302; MCP-1-R; MGC103828; MGC111760; MGC168006; CCR2_MOUSE; CCR5_HUMAN; CCR2_HUMAN; C-C chemokine receptor 5; CCR5; CC-CKR-5; CCR-5; CCCKR5; CD195; CD 195; CKR-5; CKR5; CMKBR5; FLJ78003; IDDM22; AM4-7; C C chemokine receptor type 5; C-C motif chemokine receptor 5 A159A; CC Chemokine Receptor Type 5; CCR5 chemokine(C C motif) receptor 5; Chemokine receptor CCR5; CHEMR13; HIV 1 Fusion Coreceptor; HIV1 fusion coreceptor; IDDM22; MIP-1 alpha receptor; .  
研究领域 细胞膜受体  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Mouse,  (predicted: Human, Rat, Horse, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 43 kDa
检测分子量
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse CCR2 and CCR5: 201-300/373 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009].

Function:
Receptor for the MCP-1 (JE), MCP-3 (FIC) and MCP-5 chemokines. Transduces a signal by increasing the intracellular calcium ions level.

Subunit:
Interacts with ARRB1.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Detected in monocyte/macrophage cell lines, but not in nonhematopoietic cell lines.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
P51683

Gene ID:
12772

Database links:

Entrez Gene: 12772 Mouse

Entrez Gene: 729230 Human

Entrez Gene: 60463 Rat

Omim: 601267 Human

SwissProt: P41597 Human

SwissProt: P51683 Mouse

SwissProt: O55193 Rat

Unigene: 511794 Human

Unigene: 705362 Human

Unigene: 6272 Mouse

Unigene: 211983 Rat



产品图片
Sample: Lane 1: Sp2/0 (Mouse) Cell Lysate at 30 ug Lane 2: Raw264.7 (Mouse) Cell Lysate at 30 ug Primary: Anti-CCR2 + CCR5 (bs-1671R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42-50 kD Observed band size: 50 kD
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