| 产品编号 | bs-1910R |
| 英文名称 | TGF beta Receptor III Rabbit pAb |
| 中文名称 | 转移生长因子β受体3抗体 |
| 别 名 | beta glycan; TGF beta R3; betaglycan; betaglycan proteoglycan; BGCAN; TGF beta receptor type 3; TGF-beta receptor type 3; TGF beta receptor type III; TGF-beta receptor type III; TGFB R3; TGFBR 3; TGFBR3; TGFR 3; TGFR-3; TGFR3; Transforming Growth Factor beta Receptor III; Transforming growth factor beta receptor III betaglycan 300kDa; TGF-βRⅢ; TGFβRⅢ; TGFβ RIII; TGF β RIII; TGF-β RIII; TGFβ-RIII; Transforming growth factor beta receptor type 3. |
 |
Specific References (2) | bs-1910R has been referenced in 2 publications.
111
[IF=5.191] Chao Ye. et al. Naringin in the repair of knee cartilage injury via the TGF-β/ALK5/Smad2/3 signal transduction pathway combined with an acellular dermal matrix. J Orthop Transl. 2021 Aug;: IHC ; Rabbit. 222
111
[IF=1.785] Chao Ye. et al. Naringin and bone marrow mesenchymal stem cells repair articular cartilage defects in rabbit knees through the transforming growth factor‑β superfamily signaling pathway. Exp Ther Med. 2020 Nov;20(5):1-1 IHC ; Rabbit. 222
|
| 研究领域 | 肿瘤 细胞生物 免疫学 神经生物学 信号转导 干细胞 细胞凋亡 生长因子和激素 激酶和磷酸酶 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | Human, Mouse, Rat, (predicted: Chicken, Dog, Pig, Sheep, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 94 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞膜 细胞外基质 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TGFBR3: 701-850/850 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]. Function: Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. Subunit: Interacts with TCTEX1D4. Subcellular Location: Secreted. Secreted > extracellular space. Cell membrane. Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix. Post-translational modifications: Extensively modified by glycosaminoglycan groups (GAG). Similarity: Contains 1 ZP domain. SWISS: Q03167 Gene ID: 7049 Database links: Entrez Gene: 7049 Human Entrez Gene: 21814 Mouse Omim: 600742 Human SwissProt: Q03167 Human SwissProt: O88393 Mouse Unigene: 482390 Human Unigene: 200775 Mous 转化生长因子β受体Ⅲ，TGFβRⅢ |
| 产品图片 |
Sample:
K562 Cell (Human) Lysate at 40 ug
HepG2 Cell (Human) Lysate at 40 ug
Hela Cell (Human) Lysate at 40 ug
Primary: Anti- TGF beta Receptor III (bs-1910R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 94 kD
Observed band size: 110 kD
Sample:
Lane 1: Mouse Placenta tissue lysates
Lane 2: Mouse Testis tissue lysates
Lane 3: Rat Placenta tissue lysates
Lane 4: Rat Testis tissue lysates
Lane 5: Human HepG2 cell lysates
Lane 6: Human HeLa cell lysates
Lane 7: Human A431 cell lysates
Primary: Anti-TGF beta Receptor III (bs-1910R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 94 kDa
Observed band size: 130 kDa
Independently Validated Antibody, image provided by Science Direct, badge number 029661:Formalin-fixed and paraffin embedded human kidney labeled with Anti-TGF Beta R3 Polyclonal Antibody, Unconjugated (bs-1910R) at 1:250. overnight at 25C followed by conjugation to the secondary antibody and DAB staining
|
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
