| 产品编号 | bs-1974R |
| 英文名称 | Netrin G2 Ligand Rabbit pAb |
| 中文名称 | 脑瘤相关基因抗体 |
| 别 名 | BAG; Brain tumor associated protein LRRC4; Brain tumor-associated protein BAG; Leucine rich repeat containing 4; Leucine rich repeat containing protein 4; Leucine-rich repeat-containing protein 4; Lrrc4; LRRC4_HUMAN; MGC133342; MGC133343; NAG14; Nasopharyngeal carcinoma associated gene 14 protein; Nasopharyngeal carcinoma-associated gene 14 protein; Netrin G2 ligand; Netrin-G2 ligand; NGL 2; NGL2; NGL-2; OTTHUMP00000212282; OTTHUMP00000212283; OTTHUMP00000212284. |
 |
Specific References (1) | bs-1974R has been referenced in 1 publications.
111
[IF=8.886] Jianbo Feng. et al. LRRC4 mediates the formation of circular RNA CD44 to inhibit GBM cell proliferation. Mol Ther-Nucl Acids. 2021 Aug;: WB ; Human. 222
|
| 研究领域 | 免疫学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, ) |
| 产品应用 | ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 68 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LRRC4: 501-600/653 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
This gene is significantly downregulated in primary brain tumors. The exact function of the protein encoded by this gene is unknown. Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitement of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays a important role for auditory synaptic responses. Involved in the suppression of glioma. Function: Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays a important role for auditory synaptic responses. Involved in the suppression of glioma (By similarity). Subunit: Interacts with NTNG2 (By similarity). Interacts with DLG4 (By similarity). Forms a complex with DLG4 and with NMDA receptors. Subcellular Location: Membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane. Tissue Specificity: Specifically expressed in brain. Similarity: Contains 1 Ig-like (immunoglobulin-like) domain. Contains 9 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain. SWISS: Q9HBW1 Gene ID: 64101 Database links: Entrez Gene: 64101 Human Entrez Gene: 192198 Mouse Omim: 610486 Human SwissProt: Q9HBW1 Human SwissProt: Q99PH1 Mouse Unigene: 655003 Human Unigene: 443660 Mouse Unigene: 198672 Rat |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
