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RabbitAnti-CXCL9 Rabbit pAb  antibody (bs-2551R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-2551R
英文名称 CXCL9 Rabbit pAb
中文名称 γ干扰素诱导单核细胞因子抗体
别    名 CMK; Humig; MIG; SCYB9; crg-10; CXCL9_HUMAN; CXCL9; Gamma-interferon-induced monokine; Monokine induced by interferon-gamma (HuMIG | MIG); Small-inducible cytokine B9;   
Specific References  (15)     |     bs-2551R has been referenced in 15 publications.
111 [IF=10.4] Yada, Akito, et al. "Splenectomy attenuates murine liver fibrosis with hypersplenism stimulating hepatic accumulation of Ly-6C lo macrophages."Journal of Hepatology (2015).  IHC-P ;  Mouse.  222
111 [IF=7.109] Tan Rui-zhi. et al. Macrophages mediate psoriasis via Mincle-dependent mechanism in mice. CELL DEATH DISCOV. 2023 Apr;9(1):1-13  WB ;  Mouse.  222
111 [IF=6.66] Clancy-Thompson, Eleanor, et al. "Melanoma induces, and adenosine suppresses, CXCR3-cognate chemokine production and T-cell infiltration of lungs bearing metastatic-like disease." Cancer immunology research 3.8 (2015): 956-967.  IHC-P ;  Mouse.  222
111 [IF=5.58] Zhang, Qian-Qian, et al. "CD11b deficiency suppresses intestinal tumor growth by reducing myeloid cell recruitment." Scientific reports 5 (2015).  WB ;  Mouse.  222
111 [IF=5.195] Jie Wang. et al. Huanglian Jiedu plaster ameliorated X-ray-induced radiation dermatitis injury by inhibiting HMGB1-mediated macrophage-inflammatory interaction. J ETHNOPHARMACOL. 2023 Feb;302:115917  WB, IHC ;  Human, Mouse.  222
111 [IF=4.493] Fan Jiahui. et al. Study on the Correlation between Interleukin-27 and CXCL10 in Pulmonary Tuberculosis. J IMMUNOL RES. 2022;2022:2932837  IHC ;  Human.  222
111 [IF=3.87] Cai, Zhaowei, et al. "Transcriptomic analysis of hepatic responses to testosterone deficiency in miniature pigs fed a high-cholesterol diet." BMC genomics 16.1 (2015): 59.  IHC-P ;  Pig.  222
111 [IF=3.647] Hu Sun. et al. Study on the relationship between CXCR3 and its ligands and tubal tuberculosis. Life Sci. 2021 May;272:119047  IHC ;  Human.  222
111 [IF=2.939] Yang R et al. Cordycepin Attenuates IFN-γ-Induced Macrophage IP-10 and Mig Expressions by Inhibiting STAT1 Activity in CFA-Induced Inflammation Mice Model. Inflammation. 2019 Dec 23.  IHC-P ;  Mouse.  222
111 [IF=2.495] Xin Hu. et al. The role of CXCR3 and its ligands expression in Brucellar spondylitis. Bmc Immunol. 2020 Dec;21(1):1-8  IHC ;  Human.  222
111 [IF=2.19] Sawano, Takeyuki, et al. "Fatty acid synthase-positive hepatocytes and subsequent steatosis in rat livers by irinotecan." Oncology Reports.  IHC-P ;  Rat.  222
111 [IF=2.15] Shimoura, Noriko, et al. "Interleukin (IL)-18, cooperatively with IL-23, induces prominent inflammation and enhances psoriasis-like epidermal hyperplasia." Archives of Dermatological Research (2017): 1-7.  IHC ;  Mouse.  222
111 [IF=1.851] Wakasa Y et al. Delay in hepatocyte proliferation and prostaglandin D2 synthase expression for cholestasis due to endotoxin during partial hepatectomy in rats. Mol Med Rep. 2019 Sep 13.  IHC-P ;  Rat.  222
111 [IF=1.785] Xiaoqian Shang. et al. Diagnostic value of CXCR3 and its ligands in spinal tuberculosis. Exp Ther Med. 2021 Jan;21(1):1-1  IHC ;  Human.  222
111 [IF=0] Lee et al. Establishment of a chronic obstructive pulmonary disease mouse model based on the elapsed time after LPS intranasal instillation. (2018) Lab.Anim.Res. 34:01-Oct  IHC-P ;  Mouse.  222
研究领域 肿瘤  免疫学  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Human, Mouse,  (predicted: Rat, Pig, Cow, Horse, )
产品应用 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 14 kDa
细胞定位 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CXCL9: 23-125/125 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 MIG (monokine induced by interferon-gamma), a member of the alpha-chemokine family (CXC) of cytokines, is produced by stimulated monocytes, macrophages and endothelial cells. It signals through the CXCR3 receptor. MIG selectively chemoattracts Th1 lymphocytes, and also exerts other activities including inhibition of tumor growth, angiogenesis, and inhibition of colony formation of hematopoietic progenitors. Human MIG is active on murine cells.

Function:
Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3.

Subcellular Location:
Secreted.

Similarity:
Belongs to the intercrine alpha (chemokine CxC) family.

SWISS:
Q07325

Gene ID:
4283

Database links:

Entrez Gene: 4283 Human

Omim: 601704 Human

SwissProt: Q07325 Human

Unigene: 77367 Human



产品图片
Sample: Lane 1: Recombinant mouse CXCL9 protein Primary: Anti-CXCL9 (bs-2551R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 14 kDa Observed band size: 20 kDa
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