| 产品编号 | bs-2572R |
| 英文名称 | FPR1 Rabbit pAb |
| 中文名称 | 甲酸基肽受体1抗体 |
| 别 名 | FMLP; FPR; FPR1_HUMAN; FPR1; fMLP receptor; N-formyl peptide receptor (FPR); N-formylpeptide chemoattractant receptor; |
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Specific References (3) | bs-2572R has been referenced in 3 publications.
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[IF=6.6] Ana Paula Girol. et al. Annexin A1 Mimetic Peptide and Piperlongumine: Anti-Inflammatory Profiles in Endotoxin-Induced Uveitis. Cells-Basel. 2021 Nov;10(11):3170 IHC ; Rat. 222
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[IF=4.26] Wang et al. Formylpeptide Receptors Promote the Migration and Differentiation of Rat Neural Stem Cells. (2016) Sci.Re. 6:25946 WB, IF(ICC) ; Rat. 222
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[IF=4.12] Franken et al. Splenic red pulp macrophages are intrinsically superparamagnetic and contaminate magnetic cell isolates. (2015) Sci.Rep. 5:12940 FC/FACS ; Mouse. 222
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| 研究领域 | 信号转导 转录调节因子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | Human, (predicted: Mouse, Rat, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 39 kDa |
| 检测分子量 | 60 |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FPR1: 51-150/350 <Extracellular> |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010] Function: High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Neutrophils. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P21462 Gene ID: 2357 Database links: Entrez Gene: 2357 Human Omim: 136537 Human SwissProt: P21462 Human Unigene: 753 Human 转录调节因子（Transcriptin Regulators） FPR1属于G蛋白偶联受体家族成员，参与细胞信号传导，激活MAPK通路，免疫应答。 |
| 产品图片 |
Sample:
Lane 1: U87MG (Human) Cell Lysate at 30 ug
Lane 2: U251 (Human) Cell Lysate at 30 ug
Lane 3: U937 (Human) Cell Lysate at 30 ug
Lane 4: SW480 (Human) Cell Lysate at 30 ug
Primary: Anti-FPR1 (bs-2572R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 60 kD
Observed band size: 60 kD
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
