| 产品编号 | bs-2627R |
| 英文名称 | IL28A Rabbit pAb |
| 中文名称 | 白细胞介素28A抗体 |
| 别 名 | IFNL2a; IFNL3a; IL-28A; IL28A; EG330496; If1ia1; IFNL2_HUMAN; IFNL2; IFN-lambda-2; Cytokine Zcyto20; Interleukin-28A (IL-28A); ZCYTO20; IFNL2_MOUSE; |
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Specific References (1) | bs-2627R has been referenced in 1 publications.
111
[IF=0] Wang et al. Altered Expression of IFN-λ2 in Allergic Airway Disorders and Identification of Its Cell Origins. (2016) Mediators.Inflam. 2016:5759496 FCM,IF(ICC) ; Human. 222
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| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | (predicted: Human, Mouse, Dog, Pig, Cow, Horse, ) |
| 产品应用 | ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 20 kDa |
| 检测分子量 | 20 |
| 细胞定位 | 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IL-28A: 131-200/200 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008] Function: Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Subcellular Location: Secreted. Similarity: Belongs to the lambda interferon family. SWISS: Q8IZJ0 Gene ID: 282616 Database links: Entrez Gene: 282616 Human Entrez Gene: 330496 Mouse Omim: 607401 Human SwissProt: Q8IZJ0 Human SwissProt: Q4VK74 Mouse Unigene: 567792 Human Unigene: 454510 Mouse |
| 产品图片 |
Sample:
Lane 1: Mouse Pancreas tissue lysates
Lane 2: Mouse Testis tissue lysates
Lane 3: Human MCF-7 cell lysates
Lane 4: Human HeLa cell lysates
Primary: Anti-IL28A (bs-2627R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 20 kDa
Observed band size: 20 kDa
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
