| 产品编号 | bs-3579R |
| 英文名称 | SLC40A1 Rabbit pAb |
| 中文名称 | 细胞膜铁转运蛋白FP1抗体 |
| 别 名 | FPN; FPN1; HFE4; IREG1; MST079; MSTP079; MTP1; SLC11A3; Dusg; MTP; Ol5; Pcm; Slc39a1; S40A1_HUMAN; SLC40A1; Ferroportin-1; Iron-regulated transporter 1; Solute carrier family 40 member 1; S40A1_MOUSE; Metal transporter protein 1 (MTP1); S40A1_RAT; CAR1; C |
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Specific References (3) | bs-3579R has been referenced in 3 publications.
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[IF=5.279] Yuan Zhao. et al. Chlorogenic Acid Alleviates Chronic Stress-Induced Duodenal Ferroptosis via the Inhibition of the IL-6/JAK2/STAT3 Signaling Pathway in Rats. J AGR FOOD CHEM. J Agr Food Chem. 2022;XXXX(XXX):XXX-XXX WB ; Rat. 222
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[IF=4.255] Liu et al. Synthetic Porcine Hepcidin Exhibits Different Roles in Escherichia coli and Salmonella Infections. (2017) Antimicrob.Agents.Chemother.Sep 22;61(10). WB ; ETEC K88&Salmonella enterica serovar Typhimurium CMCC 50013. 222
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[IF=2.431] Zhang J et al. Iron Dyshomeostasis Participated in Rat Hippocampus Toxicity Caused by Aluminum Chloride. Biol Trace Elem Res. 2019 Dec 17. WB ; Rat. 222
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| 研究领域 | 肿瘤 免疫学 信号转导 转录调节因子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | Human, (predicted: Mouse, Rat, Dog, Pig, Rabbit, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 63 kDa |
| 检测分子量 | 63 |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SLC40A1: 201-300/571 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
SLC40A1 may be involved in iron export from duodenal epithelial cells and also in transfer of iron between maternal and fetal circulation. It mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin). Defects in SLC40A1 are the cause of hemochromatosis type 4, an autosomal dominant iron-loading disorder characterized by early iron accumulation in reticuloendothelial cells and a marked increase in serum ferritin. Function: May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin). Subcellular Location: Cell membrane; Multi-pass membrane protein. Note=Localized to the basolateral membrane of polarized epithelial cells. Tissue Specificity: Expressed in placenta, intestine, muscle and spleen. DISEASE: Defects in SLC40A1 are the cause of hemochromatosis type 4 (HFE4) [MIM:606069]. HFE4 is an autosomal dominant iron-loading disorder characterized by early iron accumulation in reticuloendothelial cells and a marked increase in serum ferritin before elevation of the transferrin saturation. Similarity: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. SWISS: Q9NP59 Gene ID: 30061 Database links: Entrez Gene: 30061 Human Entrez Gene: 53945 Mouse Omim: 604653 Human SwissProt: Q9NP59 Human SwissProt: Q9JHI9 Mouse Unigene: 643005 Human Unigene: 28756 Mouse Unigene: 15324 Rat |
| 产品图片 |
Sample:
Embryo (Mouse) Lysate at 40 ug
Primary: Anti-SLC40A1 (bs-3579R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 63 kD
Observed band size: 63 kD
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
