| 产品编号 | bs-3662R |
| 英文名称 | WNT10B Rabbit pAb |
| 中文名称 | 信号通路WNT10B抗体 |
| 别 名 | SHFM6; STHAG8; WNT-12; Wnt12; WN10B_HUMAN; WNT10B; Protein Wnt-12; WN10B_MOUSE; Wnt-10b; Wnt10; |
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Specific References (6) | bs-3662R has been referenced in 6 publications.
111
[IF=5.5] Zhang et al. Epidermal Growth Factor Promotes Proliferation and Migration of Follicular Outer Root Sheath Cells via Wnt/β-Catenin Signaling. (2016) Cell.Physiol.Biochem. 39:360-70 IHC ; Human. 222
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[IF=4.65] Zhang, H., et al. "Epidermal Growth Factor Promotes Proliferation and Migration of Follicular Outer Root Sheath Cells via Wnt/β-Catenin Signaling."Cellular Physiology and Biochemistry 39.1 (2016): 360-370. WB ; Human. 222
111
[IF=3.553] Li M et al. Plant MIR156 Regulates Intestinal Growth in Mammals by Targeting the Wnt/β-catenin Pathway. Am J Physiol Cell Physiol. 2019 Jun 5. IHF&ICF ; Mouse&Pig. 222
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[IF=1.597] Liya Bai. et al. DNA methylation and histone acetylation are involved in Wnt10b expression during the secondary hair follicle cycle in Angora rabbits. 2021 Jan 06 IHC ; Rabbit. 222
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[IF=1.07] Ke, Jin, et al. "Erbium: YAG laser (2,940 nm) treatment stimulates hair growth through upregulating Wnt 10b and β-catenin expression in C57BL/6 mice." International Journal of Clinical and Experimental Medicine 8.11 (2015): 20883. WB ; Mouse. 222
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[IF=1.03] Lu, Juan, et al. "Expression of Wnt3a, Wnt10b, β-catenin and DKK1 in periodontium during orthodontic tooth movement in rats." Acta Odontologica Scandinavica (2015): 1-7. IHC-P ; Rat. 222
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| 研究领域 | 肿瘤 免疫学 信号转导 转录调节因子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | Human, (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 40 kDa |
| 细胞定位 | 细胞浆 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human WNT10B: 201-300/389 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region. [provided by RefSeq, Jul 2008] Subcellular Location: Secreted, extracellular space, extracellular matrix. Tissue Specificity: Detected in most adult tissues. Highest levels were found in heart and skeletal muscle. Low levels are found in brain. Similarity: Belongs to the Wnt family. SWISS: O00744 Gene ID: 7480 Database links: Entrez Gene: 7480 Human Entrez Gene: 22410 Mouse Omim: 601906 Human SwissProt: O00744 Human SwissProt: P48614 Mouse Unigene: 91985 Human Unigene: 4709 Mouse |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
