| 产品编号 | bs-3807R |
| 英文名称 | PLAA Rabbit pAb |
| 中文名称 | 磷脂酶A2激活蛋白抗体 |
| 别 名 | PLAP_HUMAN; phospholipase A-2-activating protein; PLAP; PLA2P; phospholipase A2 activating protein; DOA1; NDMSBA; |
 |
Specific References (1) | bs-3807R has been referenced in 1 publications.
111
[IF=3.71] Rosing, Katharina, et al. Everolimus therapy is associated with reduced lipoprotein-associated phospholipase A2 (Lp-Pla2) activity and oxidative stress in heart transplant recipients. Atherosclerosis. 2013 Sep;230(1):164-70. WB ; Human, Mouse. 222
|
| 研究领域 | 细胞生物 免疫学 激酶和磷酸酶 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 87 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞核 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Phospholipase A2 activator protein: 101-200/795 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Phospholipase A2 activator protein (PLAP), activates PLA2 (phospholipase A2 enzyme) and is an important mediator of eicosanoid generation. Also known as a pro-inflammatory agent, PLAP has been found in inflamed tissues and synovial fluid from patients with rheumatoid arthritis. As such, it is believed to play an important role in the regulation of inflammatory diseases. The formation of PLAP can be stimulated by IL-1 beta and TNF-alpha. SWISS: Q9Y263 Gene ID: 9373 Database links: Entrez Gene: 9373 Human Omim: 603873 Human SwissProt: Q9Y263 Human Unigene: 27182 Human 磷脂酶A2激活蛋白能激活磷脂酶A2，是类花生酸形成的一个重要中介体。作为促炎症反应剂，PLAP存在于类风湿性关节炎患者的炎症组织和滑膜液，因而被认为在炎症性疾病调控中发挥重要作用。IL-1β和TNF-α能刺激PLAP的形成。PLAP作为睾丸精原细胞瘤的标志物。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
