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RabbitAnti-Transaldolase 1 Rabbit pAb  antibody (bs-4041R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-4041R
英文名称 Transaldolase 1 Rabbit pAb
中文名称 转醛醇酶/EPS8L2抗体
别    名 Dihydroxyacetone transferase; EPS8L2; Glycerone transferase; TAL; TAL H; TALDO; TALDO1; TALDOR; TALH; Transaldolase 1; Transaldolase1; Transaldolase-1; EC 2.2.1.2; TALDO_HUMAN.  
研究领域 肿瘤  细胞生物  免疫学  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 37 kDa
检测分子量
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Transaldolase 1: 145-250/337 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis.

Function:
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

Subunit:
Homodimer.

DISEASE:
Transaldolase 1 deficiency (TALDO1 deficiency) [MIM:606003]: Results in telangiectases of the skin, hepatosplenomegaly, and enlarged clitoris. Note=The disease is caused by mutations affecting the gene represented in this entry.

SWISS:
Q9H6S3

Gene ID:
64787

Database links:

Entrez Gene: 64787 Human

Entrez Gene: 98845 Mouse

Omim: 614988 Human

SwissProt: Q9H6S3 Human

SwissProt: Q99K30 Mouse

Unigene: 55016 Human

Unigene: 27451 Mouse



Transaldolase 1称醛羧移转酶 或转二羟丙酮基酶,经研究该蛋白与多发性硬化症有关。
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