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RabbitAnti-CIAPIN1 Rabbit pAb  antibody (bs-5764R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-5764R
英文名称 CIAPIN1 Rabbit pAb
中文名称 细胞因子诱导凋亡抑制因子1
别    名 Anamorsin; CIAPIN 1; Cytokine induced apoptosis inhibitor 1; DRE2; CPIN1_HUMAN.  
研究领域 肿瘤  细胞生物  免疫学  细胞凋亡  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Human, Mouse,  (predicted: Rat, Pig, Cow, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 34 kDa
检测分子量
细胞定位 细胞核 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CIAPIN1: 51-150/312 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 CIAPIN1 (Cytokine induced apoptosis inhibitor 1) expression is dependent on growth factor stimulation. Overexpression confers resistance to apoptosis caused by IL3 deprivation. It may be required during hematopoiesis to mediate antiapoptotic effects of various cytokines. It also confers multidrug resistance in gastric cancer cells by upregulating the expression of MDR1 and MRP1.

Function:
May be required for the maturation of extramitochondrial Fe/S proteins (By similarity). Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity).

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Ubiquitously expressed. Highly expressed in heart, liver and pancreas.

Similarity:
Belongs to the anamorsin family.

SWISS:
Q6FI81

Gene ID:
57019

Database links:

Entrez Gene: 57019 Human

Entrez Gene: 109006 Mouse

Omim: 608943 Human

SwissProt: Q6FI81 Human

SwissProt: Q8WTY4 Mouse

Unigene: 4900 Human

Unigene: 27582 Mouse



产品图片
Sample: Heart (mouse) Cell Lysate at 40 ug Primary: Anti- CIAPIN1(bs-5764R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 34kD Observed band size: 36 kD
Sample: Hcclm3 (human)cell Lysate at 40 ug Primary: Anti- CIAPIN1(bs-5764R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 34kD Observed band size: 36 kD
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