产品编号 | bs-5764R |
英文名称 | CIAPIN1 Rabbit pAb |
中文名称 | 细胞因子诱导凋亡抑制因子1 |
别 名 | Anamorsin; CIAPIN 1; Cytokine induced apoptosis inhibitor 1; DRE2; CPIN1_HUMAN. |
研究领域 | 肿瘤 细胞生物 免疫学 细胞凋亡 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
克 隆 号 | |
交叉反应 | Human, Mouse, (predicted: Rat, Pig, Cow, ) |
产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 34 kDa |
检测分子量 | |
细胞定位 | 细胞核 细胞浆 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CIAPIN1: 51-150/312 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
CIAPIN1 (Cytokine induced apoptosis inhibitor 1) expression is dependent on growth factor stimulation. Overexpression confers resistance to apoptosis caused by IL3 deprivation. It may be required during hematopoiesis to mediate antiapoptotic effects of various cytokines. It also confers multidrug resistance in gastric cancer cells by upregulating the expression of MDR1 and MRP1.
Function: May be required for the maturation of extramitochondrial Fe/S proteins (By similarity). Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity). Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Ubiquitously expressed. Highly expressed in heart, liver and pancreas. Similarity: Belongs to the anamorsin family. SWISS: Q6FI81 Gene ID: 57019 Database links: Entrez Gene: 57019 Human Entrez Gene: 109006 Mouse Omim: 608943 Human SwissProt: Q6FI81 Human SwissProt: Q8WTY4 Mouse Unigene: 4900 Human Unigene: 27582 Mouse |
产品图片 |
Sample: Heart (mouse) Cell Lysate at 40 ug
Primary: Anti- CIAPIN1(bs-5764R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 34kD
Observed band size: 36 kD
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1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |