| 产品编号 | bs-5796R |
| 英文名称 | BCL2L10 Rabbit pAb |
| 中文名称 | BCL2样10促凋亡蛋白抗体 |
| 别 名 | Anti apoptotic protein NrH; Anti-apoptotic protein NrH; Apoptosis regulator Bcl B; Apoptosis regulator Bcl-B; B2L10_HUMAN; BCL B; Bcl-2-like protein 10; Bcl2 L 10; BCL2 like 10(apoptosis facilitator); BCL2 like 10 protein; Bcl2-L-10; Bcl2l10; BCLB; Boo; D |
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Specific References (3) | bs-5796R has been referenced in 3 publications.
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[IF=5.572] Shaohua Hou. et al. Design, synthesis and biological evaluation of 1H-indazole derivatives as novel ASK1 inhibitors. Eur J Med Chem. 2021 Aug;220:113482 WB ; Human. 222
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[IF=1.986] Huang,et al.Role of BCL2L10 in regulating buffalo (Bubalus bubalis) oocyte maturation.(2018) Theriogenology. 110:1-7. IHC-P + IF(ICC) ; Buffalo. 222
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[IF=0.219] Wang,et al.Yisui shengxue granule, a traditional Chinese medicine compound preparation, can up-regulate the expression of GM-CSF and its receptor in mice bone marrow after irradiation.(2017) Biomedical Research. 28:. ICC ; Mouse. 222
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| 研究领域 | 肿瘤 细胞生物 免疫学 细胞凋亡 肿瘤细胞生物标志物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Rabbit, ) |
| 产品应用 | ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 22 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞核 细胞浆 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human BCL2L10: 101-194/194 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. BCL2L10 is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human BCL2L10 protein is widely expressed. Also, the human BCL2L10 functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1. Function: Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK. Subunit: Binds to Bcl-2, Bcl-X and BAX. Interacts with APAF1. Subcellular Location: Mitochondrion. Nucleus membrane. Tissue Specificity: Widely expressed in adult tissues. Similarity: Belongs to the Bcl-2 family. SWISS: Q9HD36 Gene ID: 10017 Database links: Entrez Gene: 10017 Human Omim: 606910 Human SwissProt: Q9HD36 Human Unigene: 283672 Human |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
