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RabbitAnti-Fast Myosin Skeletal Heavy chain Rabbit pAb  antibody (bs-5885R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-5885R
英文名称 Fast Myosin Skeletal Heavy chain Rabbit pAb
中文名称 肌球蛋白重链抗体
别    名 heavy chain Myosin; adult 1; MGC133384; Myh 1; Myh1; MYH1_HUMAN; Myosin heavy chain; Myosin heavy chain IIx/d; Myosin heavy chain skeletal muscle adult 1; Myosin light chain 1 alkali skeletal fast; Myosin-1; Myosin1; skeletal muscle; MYHa; MyHC-2x; MyHC-2  
Specific References  (5)     |     bs-5885R has been referenced in 5 publications.
111 [IF=7.014] Kong D et al. MiR-17 and miR-19 cooperatively promote skeletal muscle cell differentiation. Cell Mol Life Sci. 2019 Jun 18.  ICF ;  Human.  222
111 [IF=4.755] Zhang Lijiao. et al. Dysregulated myokines and signaling pathways in skeletal muscle dysfunction in a cigarette smoke–induced model of chronic obstructive pulmonary disease. FRONT PHYSIOL. 2022 Aug;0:1600  IHC, WB ;  Mouse.  222
111 [IF=2.674] Tugeqin Bou. et al. Fast and slow myofiber-specific expression profiles are affected by noncoding RNAs in Mongolian horses. Comp Biochem Phys D. 2022 Mar;41:100942  IHC ;  Horses.  222
111 [IF=2.573] Bao T et al. The distinct transcriptomes of fast-twitch and slow-twitch muscles in Mongolian horses. Comp Biochem Physiol Part D Genomics Proteomics. 2019 Dec 11;33:100649.  IHC-P ;  Horse.  222
111 [IF=1.673] T. Gomi. et al. Comprehensive histological investigation of age-related changes in dermal extracellular matrix and muscle fibers in the upper lip vermilion.. Int J Cosmetic Sci. 2020 Aug;42(4):359-368  IF ;  Rat.  222
研究领域 肿瘤  细胞生物  信号转导  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, )
产品应用 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 223 kDa
检测分子量
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Myosin heavy chain 1: 901-1000/1939 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. Myosin heavy chains are encoded by a multigene family. In mammals at least 10 different myosin heavy chain (MYH) isoforms have been described from striated, smooth, and nonmuscle cells. These isoforms show expression that is spatially and temporally regulated during development. [provided by RefSeq, Jul 2008].

Function:
Muscle contraction.

Subunit:
Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2).

Subcellular Location:
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.

Similarity:
Contains 1 IQ domain.
Contains 1 myosin head-like domain.

SWISS:
P12882

Gene ID:
4619

Database links:

Entrez Gene: 281337 Cow

Entrez Gene: 4619 Human

Entrez Gene: 17879 Mouse

Entrez Gene: 287408 Rat

Omim: 160730 Human

Omim: 160740 Human

SwissProt: Q9BE40 Cow

SwissProt: P12882 Human

SwissProt: Q5SX40 Mouse

SwissProt: Q9TV61 Pig

Unigene: 689619 Human

Unigene: 477065 Mouse



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