| 产品编号 | bs-2928R |
| 英文名称 | PDLIM3 Rabbit pAb |
| 中文名称 | 辅肌动蛋白相关LIM蛋白抗体 |
| 别 名 | ALP; Actinin associated LIM protein; Actinin-associated LIM protein; alpha actinin 2 associated LIM protein; alpha-actinin-2-associated LIM protein; DKFZp686L0362; Enigma homolog; PDLI3_HUMAN; PDLIM 3; PDLIM-3; PDLIM3; PDZ and LIM domain 3; PDZ and LIM do |
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Specific References (1) | bs-2928R has been referenced in 1 publications.
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[IF=4.818] Hu Xinpeng. et al. Comprehensive Analysis of PDLIM3 Expression Profile, Prognostic Value, and Correlations with Immune Infiltrates in Gastric Cancer. J IMMUNOL RES. 2022;2022:2039447 IHC ; Human. 222
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| 研究领域 | 细胞生物 免疫学 信号转导 细胞骨架 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, ) |
| 产品应用 | ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 39 kDa |
| 检测分子量 | |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PDLIM3: 301-364/364 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy. Function: May play a role in the organization of actin filament arrays within muscle cells. Subunit: Interacts with ACTN2. Subcellular Location: Cytoplasm, myofibril, sarcomere, Z line. Note=Localizes to myofiber Z-lines. Tissue Specificity: Isoform 1 is highly expressed in differentiated skeletal muscle. Isoform 2 is heart-specific. Similarity: Contains 1 LIM zinc-binding domain. Contains 1 PDZ (DHR) domain. SWISS: Q53GG5 Gene ID: 27295 Database links: Entrez Gene: 27295 Human Entrez Gene: 53318 Mouse Omim: 605889 Human SwissProt: Q53GG5 Human SwissProt: O70209 Mouse Unigene: 442702 Human Unigene: 731826 Human Unigene: 282900 Mouse Unigene: 13361 Rat |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
