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RabbitAnti-Apg10 Rabbit pAb  antibody (bs-5991R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-5991R
英文名称 Apg10 Rabbit pAb
中文名称 自噬相关蛋白10抗体
别    名 Apg 10; Apg-10; APG 10L; APG10 autophagy 10 like; APG10 like; APG10-like; APG10L; ATG 10; ATG10; ATG10 autophagy related 10 homolog(S. cerevisiae); ATG10 autophagy related 10 homolog; ATG10_HUMAN; Autophagy related protein 10; Autophagy-related protein 10; Ubiquitin-like-conjugating enzyme ATG10  
研究领域 肿瘤  心血管  细胞生物  免疫学  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 (predicted: Human, Mouse, Rat, Cow, )
产品应用 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 25 kDa
检测分子量
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Apg10: 151-220/220 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3.

Function:
E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3 (By similarity).

Subunit:
Interacts with MAP1LC3A. By interacting with MAP1LC3A, it plays a role in the conjugation of ATG12 to ATG5. Also able to directly interact either with ATG5 or ATG7.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the ATG10 family.

SWISS:
Q9H0Y0

Gene ID:
83734

Database links:

Entrez Gene: 83734 Human

Entrez Gene: 66795 Mouse

Entrez Gene: 688555 Rat

Omim: 610800 Human

SwissProt: Q9H0Y0 Human

SwissProt: Q8R1P4 Mouse

Unigene: 713698 Human

Unigene: 235385 Mouse

Unigene: 21798 Rat



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