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RabbitAnti-RDH11 Rabbit pAb  antibody (bs-6214R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-6214R
英文名称 RDH11 Rabbit pAb
中文名称 视黄醇脱氢酶11/丙型肝炎病毒核心蛋白抗体
别    名 CGI 82; RALR1; Androgen regulated short chain dehydrogenase/reductase 1; ARSDR1; HCBP12; HCV core binding protein; HCV core binding protein HCBP12; MDT1; Prostate short chain dehydrogenase/reductase 1; PSDR1; Retinal reductase 1; retinol dehydrogenase 11(all trans/9 cis/11 cis); Retinol dehydrogenase 11; SCALD; SDR7C1; Short chain dehydrogenase/reductase family 7C, member 1; RDH11_HUMAN.  
Specific References  (1)     |     bs-6214R has been referenced in 1 publications.
111 [IF=4.366] Jae Yeon Kim. et al. PEDF-Mediated Mitophagy Triggers the Visual Cycle by Enhancing Mitochondrial Functions in a H2O2-Injured Rat Model. Cells-Basel. 2021 May;10(5):1117  IHC ;  Rat.  222
研究领域 神经生物学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, Sheep, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 35 kDa
检测分子量
细胞定位 细胞浆 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RDH11: 31-130/318 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is an NADPH-dependent retinal reductase and a short-chain dehydrogenase/reductase. The encoded protein has no steroid dehydrogenase activity.

Function:
Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity towards 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected.

Subcellular Location:
Endoplasmic reticulum membrane; Single-pass type II membrane protein.

Tissue Specificity:
Predominantly expressed in the epithelial cells of prostate, in both basal and luminal secretory cell populations. Expressed at low levels in spleen, thymus, testis, ovary, small intestine, colon, peripherical blood leukocytes, kidney, adrenal gland and fetal liver. Not detected in prostatic fibromuscular stromal cells, endothelial cells, or infiltrating lymphocytes.

Post-translational modifications:
Not glycosylated.

Similarity:
Belongs to the short-chain dehydrogenases/reductases (SDR) family.

SWISS:
Q8TC12

Gene ID:
51109

Database links:

Entrez Gene: 51109 Human

Omim: 607849 Human

SwissProt: Q8TC12 Human

Unigene: 226007 Human

Unigene: 719925 Human



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