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RabbitAnti-SCYL1BP1 Rabbit pAb antibody (bs-6643R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-6643R
英文名称 SCYL1BP1 Rabbit pAb
中文名称 SCYL结合蛋白1抗体
别    名 GO; NTKLBP1; SCYL1BP1; NTKL-BP1; SCYL1-BP1; GORAB_HUMAN; GORAB; N-terminal kinase-like-binding protein 1 (NTKL-BP1 | NTKL-binding protein 1 | hNTKL-BP1); SCY1-like 1-binding protein 1 (SCYL1-BP1 | SCYL1-binding protein 1); GORAB_MOUSE; N-terminal kinase-like-binding protein 1 (NTKL-BP1 | NTKL-binding protein 1 | mNTKL-BP1); GORAB_RAT; N-terminal kinase-like-binding protein 1 (NTKL-BP1 | NTKL-binding protein 1); golgin, RAB6 interacting; SCY1-like 1 binding protein 1; golgin, RAB6-interacting; gerodermia osteodysplastica; RAB6-interacting golgin  
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 45kDa
检测分子量 55
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SCYL1BP1: 201-300/394 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Defects in GORAB are the cause of geroderma osteodysplasticum (GO) [MIM:231070]; also known as gerodermia osteodysplastica or Walt Disney dwarfism. GO is a rare autosomal recessive disorder characterized by lax, wrinkled skin, joint laxity and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia and a variable degree of growth retardation.

Subunit:
Interacts with SCYL1 (By similarity). Interacts with RCHY1 and RAB6A/RAB6.

Subcellular Location:
Cytoplasm. Golgi apparatus.

DISEASE:
Defects in GORAB are the cause of geroderma osteodysplasticum (GO) [MIM:231070]; also known as gerodermia osteodysplastica or Walt Disney dwarfism. GO is a rare autosomal recessive disorder characterized by lax, wrinkled skin, joint laxity and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia and a variable degree of growth retardation.

Similarity:
Belongs to the GORAB family.

SWISS:
Q5T7V8

Gene ID:
92344

Database links:

Entrez Gene: 92344 Human

Entrez Gene: 98376 Mouse

Entrez Gene: 304923 Rat

Omim: 607983 Human

SwissProt: Q5T7V8 Human

SwissProt: Q8BRM2 Mouse

SwissProt: B1H222 Rat

Unigene: 183702 Human

Unigene: 32901 Mouse

Unigene: 45710 Rat



产品图片
Sample: HepG2 Cell (Human) Lysate at 40 ug Primary: Anti-SCYL1BP1 (bs-6643R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 45 kD Observed band size: 55 kD
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