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RabbitAnti-ORP8 Rabbit pAb  antibody (bs-6334R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-6334R
英文名称 ORP8 Rabbit pAb
中文名称 氧化固醇结合蛋白8抗体
别    名 MST120; MSTP120; ORP 8; OSBP related protein 8; OSBP10; OSBPL8; Oxysterol binding protein like 8; Oxysterol binding protein like protein 8; Oxysterol binding protein related protein 8; OSBL8_HUMAN.  
研究领域 心血管  细胞生物  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, )
产品应用 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 101 kDa
检测分子量
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ORP8: 121-220/889 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 ORP8 is a member of the oxysterol-binding protein related protein family. In humans, the gene family consists of 12 members, and extensive splice variation increases the number of encoded protein products substantially. The ORPs have been implicated as sterol sensors that regulate a number of cellular functions including sterol and neutral lipid metabolism, intracellular lipid transport, membrane trafficking and cell signaling. ORP8 has been recently shown to act as a sterol sensor that affects the reverse cholesterol transport process via modulation of ABCA1 expression and macrophage cholesterol efflux.

Subcellular Location:
Endoplasmic reticulum

Tissue Specificity:
Widely expressed.

Similarity:
Belongs to the OSBP family.
Contains 1 PH domain.

SWISS:
Q9BZF1

Gene ID:
114882

Database links:

Entrez Gene: 114882 Human

Entrez Gene: 237542 Mouse

Omim: 606736 Human

SwissProt: Q9BZF1 Human

SwissProt: B9EJ86 Mouse

Unigene: 220204 Mouse



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