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RabbitAnti-PHAPI2 Rabbit pAb  antibody (bs-6769R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-6769R
英文名称 PHAPI2 Rabbit pAb
中文名称 酸性核磷蛋白32家族B抗体
别    名 Acidic(leucine rich) nuclear phosphoprotein 32 family member B; Acidic leucine rich nuclear phosphoprotein 32 family member B; Acidic leucine-rich nuclear phosphoprotein 32 family member B; Acidic nuclear phosphoprotein 32 family member B; Acidic protein rich in leucines; AN32B_HUMAN; ANP 32B; ANP32B; APRIL; PAL 31; PAL31; PHAPI 2; PHAPI2; PHAPI2 protein; PHAPI2a; Proliferation related acidic leucine rich protein; Putative HLA-DR-associated protein I-2; Silver stainable protein SSP 29; Silver stainable protein SSP29; Silver-stainable protein SSP29; Ssp 29; Ssp29.  
研究领域 细胞生物  信号转导  细胞凋亡  细胞周期蛋白  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Dog, Zebrafish, Sheep,  (predicted: Human, Mouse, Rat, Cow, Fruit Fly, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 29 kDa
检测分子量
细胞定位 细胞核 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PHAPI2/APRIL: 51-150/251 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.

Function:
Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.

Subunit:
Monomer. Interacts with histones H3 and H4.

Subcellular Location:
Isoform 1: Nucleus. Note=Accumulates in the nuclei at the S phase (By similarity).
Isoform 2: Cytoplasm. Note=Lacks a nuclear localization signal.

Tissue Specificity:
Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.

Post-translational modifications:
Some glutamate residues are glycylated by TTLL8. This modification occurs exclusively on glutamate residues and results in a glycine chain on the gamma-carboxyl group (By similarity).

Similarity:
Belongs to the ANP32 family.
Contains 4 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.

SWISS:
Q92688

Gene ID:
10541

Database links:

Entrez Gene: 10541 Human

Entrez Gene: 67628 Mouse

Entrez Gene: 170724 Rat

SwissProt: Q92688 Human

SwissProt: Q9EST5 Mouse

SwissProt: Q9EST6 Rat

Unigene: 494604 Human

Unigene: 263913 Mouse

Unigene: 20465 Rat



产品图片
Sample: Jurkat(Human) Cell Lysate at 30 ug Primary: Anti-PHAPI2 (bs-6769R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 29 kD Observed band size: 29 kD
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