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RabbitAnti-IL-4I1 Rabbit pAb  antibody (bs-6841R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-6841R
英文名称 IL-4I1 Rabbit pAb
中文名称 白细胞介素4诱导蛋白1抗体
别    名 IL4I1; hFIG1; IL4 induced protein 1; IL-4 induced protein 1; Interleukin 4 induced protein 1; LAAO; FIG 1; Fig 1 protein; FIG1; Fig1 protein; hFIG 1; hFIG1; IL4-induced protein 1; Interleukin 4 induced 1; Interleukin four induced 1; Interleukin-4-induced protein 1; L amino acid oxidase; L-amino-acid oxidase; LAAO; LAO; Protein Fig 1; Protein Fig-1; Protein Fig1; OXLA_HUMAN.  
研究领域 细胞生物  细胞凋亡  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Mouse, Rat,  (predicted: Human, Dog, Pig, Sheep, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 61 kDa
检测分子量
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IL-4I1: 51-160/567 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].

Function:
Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation (By similarity).

Subcellular Location:
Isoform 1: Lysosome (By similarity).
Isoform 2: Lysosome (By similarity).

Tissue Specificity:
Isoform 1 is primarily found in immune tissues.

Similarity:
Belongs to the flavin monoamine oxidase family. FIG1 subfamily.

SWISS:
Q96RQ9

Gene ID:
259307

Database links:

Entrez Gene: 259307 Human

Entrez Gene: 14204 Mouse

Omim: 609742 Human

SwissProt: Q1WMJ3 Human

SwissProt: Q96RQ9 Human

SwissProt: O09046 Mouse

Unigene: 27567 Mouse



产品图片
Paraformaldehyde-fixed, paraffin embedded (rat spleen); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (IL-4I1) Polyclonal Antibody, Unconjugated (bs-6841R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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