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RabbitAnti-S100 alpha 2 Rabbit pAb  antibody (bs-7873R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-7873R
英文名称 S100 alpha 2 Rabbit pAb
中文名称 S100A2抗体
别    名 S100 calcium binding protein A2; CAN19; MGC111539; Protein S 100L; Protein S-100L; Protein S100 A2; Protein S100-A2; Protein S100L; S100 A2; S100 calcium-binding protein A2; S100A2; S100L; S10A2_HUMAN.  
Specific References  (1)     |     bs-7873R has been referenced in 1 publications.
111 [IF=1.39] Wu et al. A retrospective, single-center cohort study on 65 patients with primary retroperitoneal liposarcoma. (2018) Oncol.Lett. 15:1799-1810  IHC-P ;  Human.  222
研究领域 肿瘤  细胞生物  信号转导  细胞周期蛋白  结合蛋白  细胞分化  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Goat, Cat, ,lizard)
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 11 kDa
检测分子量
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human S100 alpha 2: 20-98/98 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is a member of the S100family of proteins containing 2 EF-hand calcium-binding motifs.S100 proteins are localized in the cytoplasm and/or nucleus of awide range of cells, and involved in the regulation of a number ofcellular processes such as cell cycle progression anddifferentiation. S100 genes include at least 13 members which arelocated as a cluster on chromosome 1q21. This protein may have atumor suppressor function. Chromosomal rearrangements and alteredexpression of this gene have been implicated in breast cancer.

Function:
May act as a modulator against excess calciumaccumulation in normal human mammary epithelial cells. May alsoplay a role in suppressing tumor cell growth.

Subunit:
Homodimer. Interacts with FKBP4.

Tissue Specificity:
A subset of epithelial cells including normalhuman mammary epithelial cells and keratinocytes.

Similarity:
Belongs to the S-100 family
Contains 2 EF-hand domains.

SWISS:
P29034.3

Gene ID:
6273

Database links:
UniProtKB/Swiss-Prot: P29034.3

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