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RabbitAnti-CEE Rabbit pAb  antibody (bs-6405R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-6405R
英文名称 CEE Rabbit pAb
中文名称 跨膜结构域边缘蛋白CEE抗体
别    名 C7orf20; CDG2Y; CEE; CGI-20; TRC35; GET4_HUMAN; GET4; Conserved edge-expressed protein; Transmembrane domain recognition complex 35 kDa subunit (TRC35);   
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 36 kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CEE: 65-110/327 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Get4 is a 327 amino acid cytoplasmic protein that exists as two alternatively spliced isoforms. Get4 forms a multiprotein complex, known as the BAT3 complex, with UBL4A, BAT3 and ARSA. The BAT3 complex plays a role in transporting tail-anchored membrane proteins to the endoplasmic reticulum membrane. The gene encoding Get4 maps to human chromosome 7p22.3. Human chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

Function:
Component of the BAT3 complex, a multiprotein complexinvolved in the post-translational delivery of tail-anchored (TA)membrane proteins to the endoplasmic reticulum membrane. TAmembrane proteins, also named type II transmembrane proteins,contain a single C-terminal transmembrane region. The complex actsby facilitating TA proteins capture by ASNA1/TRC40: it is recruitedto ribosomes synthesizing membrane proteins, interacts with thetransmembrane region of newly released TA proteins, and transfersthem to ASNA1/TRC40 for targeting.

Subunit:
Component of the BAT3 complex, at least composed ofBAG6/BAT3, UBL4A and GET3/TRC35.

Subcellular Location:
Cytoplasm, cytosol.

Similarity:
Belongs to the GET4 family.

SWISS:
Q7L5D6

Gene ID:
51608

Database links:

Entrez Gene: 51608 Human

Omim: 612056 Human

SwissProt: Q7L5D6 Human

Unigene: 107387 Human



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