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RabbitAnti-BPIL3 Rabbit pAb  antibody (bs-8425R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-8425R
英文名称 BPIL3 Rabbit pAb
中文名称 杀菌/通透性增加蛋白样3抗体
别    名 BPIB6_HUMAN; BPIFB6; Bactericidal/permeability-increasing protein-like 3; BPIL3; LPLUNC6;   
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Human,  (predicted: Mouse, Pig, Cow, Horse, Sheep, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 48 kDa
检测分子量 45
细胞定位 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BPIL3: 1-100/453 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Members of the bactericidal/permeability-increasing protein family have antimicrobial properties and bind lipophilic substances, therefore targeting gram-negative bacteria. The bactericidal permeability increasing protein (BPI) is an antibacterial and endotoxin-neutralizing molecule that is abundant in the granules of polymorphonuclear leukocytes (neutrophil granules). Sharing structural and sequence homologies with BPI, BPIL3 (Bactericidal/permeability-increasing protein-like 3) is a 453 amino acid secreted protein that contains the family’s common conserved feature of two cysteine residues that are critical for protein function. While BPIL3 is primarily expressed at low levels in tonsils, it has been found to be upregulated in hypertrophic tonsil tissue, suggesting that it may play a role in the pathogenesis of inflamed disease tissue.

Subcellular Location:
Secreted (By similarity).

Tissue Specificity:
Detected at very low levels in normal tonsils, and at higher levels in hypertrophic tonsils.

Similarity:
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

SWISS:
Q8NFQ5

Gene ID:
128859

Database links:
UniProtKB/Swiss-Prot: Q8NFQ5.1

产品图片
Sample:A549 (Human)cell Lysate at 40 ug Primary: Anti-BPIL3(bs-8425R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 48kD Observed band size: 45kD
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