| 产品编号 | bs-8467R |
| 英文名称 | FBXL3 Rabbit pAb |
| 中文名称 | FBXL3蛋白抗体 |
| 别 名 | FBL3; FBL3A; FBXL3A; IDDSFAS; FBK; Ovtm; Play68; FBXL3_HUMAN; FBXL3; F-box and leucine-rich repeat protein 3A; F-box/LRR-repeat protein 3A; FBXL3_MOUSE; Protein after-hours; Protein overtime; Afh; |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, ) |
| 产品应用 | WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 49 kDa |
| 细胞定位 | 细胞核 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FBXL3: 151-250/428 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation. Function: Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation. Subunit: Part of a SCF (SKP1-cullin-F-box) protein ligase complex. Interacts with CRY1 and CRY2. Subcellular Location: Nucleus. Cytoplasm. Predominantly nuclear. Tissue Specificity: Widely expressed. Similarity: Contains 1 F-box domain. Contains 7 LRR (leucine-rich) repeats. SWISS: Q9UKT7 Gene ID: 26224 Database links: Entrez Gene: 26224 Human Entrez Gene: 50789 Mouse Omim: 605653 Human SwissProt: Q9UKT7 Human SwissProt: Q8C4V4 Mouse Unigene: 508284 Human Unigene: 214746 Mouse |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
