| 产品编号 | bs-9214R |
| 英文名称 | SERPINB3 Rabbit pAb |
| 中文名称 | 丝氨酸蛋白酶抑制剂B3抗体 |
| 别 名 | HsT1196; Protein T4 A; Protein T4-A; SCC; SCCA PD; SCCA-1; SCCA1; SCCAPD; Serine(or cysteine) proteinase inhibitor clade B(ovalbumin) member 3; Serpin B3; Serpin peptidase inhibitor clade B(ovalbumin) member 3; SERPINB3; SPB3_HUMAN; Squamous cell carcinoma antigen 1; T4 A; T4A. |
| 研究领域 | 细胞生物 激酶和磷酸酶 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | (predicted: Human, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 46 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞浆 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SERPINB3: 71-170/390 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase.SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma. Function: May act as a protease inhibitor to modulate the host immune response against tumor cells. Subcellular Location: Cytoplasm. Seems to also be secreted in plasma by cancerous cells but at a low level. Tissue Specificity: Squamous cells. Expressed in some hepatocellular carcinoma (at protein level). Similarity: Belongs to the serpin family. Ov-serpin subfamily. SWISS: P29508 Gene ID: 6317 Database links: Entrez Gene: 6317 Human Omim: 600517 Human SwissProt: P29508 Human Unigene: 227948 Human |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
