| 产品编号 | bs-9242R |
| 英文名称 | RNF34 Rabbit pAb |
| 中文名称 | 环指蛋白34抗体 |
| 别 名 | CARP-1; CARP1; RFI; RIF; RIFF; hRFI; Momo; RNF34_BOVIN; RNF34; RING finger protein 34; RING-type E3 ubiquitin transferase RNF34; 2.3.2.27; RNF34_HUMAN; Caspase regulator CARP1; Caspases-8 and -10-associated RING finger protein 1 (CARP-1); FYVE-RING finger |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, ) |
| 产品应用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 42 kDa |
| 细胞定位 | 细胞核 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RNF34: 21-120/372 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Has E3 ubiquitin-protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Protects cells against apoptosis induced by TNF. Binds phosphatidylinositol-5-phosphate and phosphatidylinositol-3-phosphate. Function: Has E3 ubiquitin-protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Protects cells against apoptosis induced by TNF. Binds phosphatidylinositol 5-phosphate and phosphatidylinositol 3-phosphate. Subunit: Interacts with DNAJA3 (Potential). Interacts with CASP8 and CASP10. Subcellular Location: Nucleus speckle. Endomembrane system; Peripheral membrane protein. Tissue Specificity: Ubiquitous. Detected in heart, brain, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, colon and leukocytes. Post-translational modifications: Auto-ubiquitinated (in vitro) (By similarity). Proteolytically cleaved by caspases upon induction of apoptosis by TNF. Similarity: Contains 1 FYVE-type zinc finger. Contains 1 RING-type zinc finger. Contains 2 SAP domains. SWISS: Q969K3 Gene ID: 80196 Database links: Entrez Gene: 80196 Human Entrez Gene: 80751 Mouse Omim: 608299 Human SwissProt: Q969K3 Human SwissProt: Q99KR6 Mouse Unigene: 292804 Human Unigene: 388529 Mouse Unigene: 14904 Rat |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
