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RabbitAnti-C1QTNF10 Rabbit pAb  antibody (bs-9793R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-9793R
英文名称 C1QTNF10 Rabbit pAb
中文名称 补体C1q和肿瘤坏死因子相关蛋白10抗体
别    名 C1QTNF10; CTRP10; Adii; C1QL2_HUMAN; C1QL2; C1q and tumor necrosis factor-related protein 10 (C1q/TNF-related protein 10); C1QL2_MOUSE; C1q and tumor necrosis factor-related protein 10 (C1q/TNF-related protein 10 | C1qTNF10 | CTRP10);   
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Sheep, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 27 kDa
细胞定位 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human C1QL2/C1QTNF10: 101-187/187 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 C1qL2, also known as CTRP10 or C1QTNF10, is a 287 amino acid secreted protein that contains one C1q domain and one collagen-like domain. C1qL2 belongs to a large family of multimeric proteins with a signature globular domain homologous to C1QA. These proteins also share structural homology with TNF family members. The gene that encodes C1qL2 consists of approximately 2,653 bases and maps to human chromosome 2q14.2. Consisting of 237 million bases, chromosome 2 encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome, is due to mutations in the ALMS1 gene.

Function:
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity).

Subunit:
Forms homotrimers which can further assemble to form higher-order oligomeric complexes (By similarity). Interacts with BAI3 (By similarity). May interact with FAM132B (By similarity).

Subcellular Location:
Secreted.

Similarity:
Contains 1 C1q domain.
Contains 1 collagen-like domain.

SWISS:
Q7Z5L3

Gene ID:
165257

Database links:

Entrez Gene: 165257 Human

Entrez Gene: 226359 Mouse

Omim: 614330 Human

SwissProt: Q7Z5L3 Human

SwissProt: Q8CFR0 Mouse

Unigene: 433493 Human

Unigene: 337409 Mouse



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