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RabbitAnti-SLC35C2 Rabbit pAb  antibody (bs-12118R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-12118R
英文名称 SLC35C2 Rabbit pAb
中文名称 溶质载体蛋白家族35成员C2抗体
别    名 BA394O2.1; C20orf5; CGI-15; FLJ37039; MGC20633; MGC32079; MGC39183; Ovarian cancer-overexpressed gene 1 protein; OVCOV1; S35C2_HUMAN; SLC35C2; Solute carrier family 35 member C2.  
研究领域 肿瘤  心血管  细胞生物  神经生物学  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 40 kDa
检测分子量
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC35C2: 81-200/365 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 SLC35C2 (solute carrier family 35, member C2), also known as C20orf5, OVCOV1 or CGI-15, is a 365 amino acid multi-pass membrane protein that belongs to the TPT transporter family and exists as multiple alternatively spliced isoforms. Expressed ubiquitously and functionally induced in hypoxic trophoblast cells, SLC35C2 plays a role in the cellular response to tissue hypoxia and is thought to be involved in the pathogenesis of ovarian cancer. The gene encoding SLC35C2 maps to human chromosome 20, which houses over 600 genes some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.

Function:
May play an important role in the cellular response to tissue hypoxia.

Subcellular Location:
Membrane.

Tissue Specificity:
Ubiquitously expressed although the level of expression is tissue dependent. Overexpressed in ovarian cancer.

Similarity:
Belongs to the TPT transporter family. SLC35C subfamily.

SWISS:
Q9NQQ7

Gene ID:
51006

Database links:

Entrez Gene: 514485 Cow

Entrez Gene: 609863 Dog

Entrez Gene: 100056733 Horse

Entrez Gene: 51006 Human

Entrez Gene: 228875 Mouse

Entrez Gene: 100152375 Pig

Entrez Gene: 100349356 Rabbit

Entrez Gene: 311637 Rat

Entrez Gene: 323482 Zebrafish

SwissProt: Q9NQQ7 Human

SwissProt: Q8VCX2 Mouse

Unigene: 593344 Human



产品图片
Sample: Lane 1: Mouse Liver tissue lysates Lane 2: Mouse Cerebrum tissue lysates Lane 3: Rat Large intestine tissue lysates Lane 4: Rat Cerebrum tissue lysates Primary: Anti-SLC35C2 (bs-12118R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kDa Observed band size: 48 kDa
Sample: A549 Cell (Human) Lysate at 30 ug Primary: Anti-SLC35C2 (bs-12118R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kD Observed band size: 40 kD
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