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RabbitAnti-C1QL3 Rabbit pAb  antibody (bs-15083R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-15083R
英文名称 C1QL3 Rabbit pAb
中文名称 补体C1qL3链多肽抗体
别    名 C1QTNF13; C1ql; CTRP13; K100; 1110065A22Rik; Adij; C1QL3_HUMAN; C1QL3; C1q and tumor necrosis factor-related protein 13 (C1q/TNF-related protein 13); C1QL3_MOUSE; C1q and tumor necrosis factor-related protein 13 (C1q/TNF-related protein 13 | CTRP13); Glia  
Specific References  (1)     |     bs-15083R has been referenced in 1 publications.
111 [IF=4.831] Zhang Q et al. CTRP13 attenuates the expression of LN and CAV-1 Induced by high glucose via CaMKKβ/AMPK pathway in rLSECs. Aging (Albany NY). 2020 Jun 17;12(12):11485-11499.  IHC-P&WB ;  Rat.  222
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Rat,  (predicted: Human, Mouse, Chicken, Dog, Pig, Cow, Horse, Sheep, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 25 kDa
细胞定位 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human C1QL3: 131-225/225 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 C1QL3 (Complement C1q Like 3) is a Protein Coding gene. An important paralog of this gene is C1QL1.

Function:
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). Plays a role in glucose homeostasis. Via AMPK signaling pathway, stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, reduces the expression of gluconeogenic enzymes G6PC and PCK1 and hence decreases de novo glucose production (By similarity).

Subunit:
Interacts with BAI3 (By similarity).

Subcellular Location:
Secreted (Potential).

Similarity:
Contains 1 C1q domain.
Contains 1 collagen-like domain.

SWISS:
Q5VWW1

Gene ID:
389941

Database links:

Entrez Gene: 389941 Human

Entrez Gene: 227580 Mouse

SwissProt: Q5VWW1 Human

SwissProt: Q9ESN4 Mouse

Unigene: 676792 Human

Unigene: 727706 Human

Unigene: 229322 Mouse

Unigene: 477072 Mouse



产品图片
Paraformaldehyde-fixed, paraffin embedded (rat liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (C1QL3) Polyclonal Antibody, Unconjugated (bs-15083R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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