| 产品编号 | bs-15135R |
| 英文名称 | C22orf29 Rabbit pAb |
| 中文名称 | 22号染色体开放阅读框29抗体 |
| 别 名 | BOP; C22orf29; BOP_HUMAN; RTL10; BH3-only protein; Retrotransposon Gag-like protein 10; |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | Human, |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 39 kDa |
| 检测分子量 | 45 |
| 细胞定位 | 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human C22orf29: 21-100/364 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Chromosome 22 contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translo-acations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein, Bcr-Abl, a potent cell proliferation activator found in several types of leukemia. The C22orf29 gene product has been provisionally designated C22orf29 pending further characterization Function: Could induce apoptosis in a BH3 domain-dependent manner.The direct interaction network of Bcl-2 family members may play akey role in modulation BOP intrinsic apoptotic signaling activity. Subunit: Interacts (via BH3 domain) with VDAC1. Interacts withpro-survival Bcl-2 family members, BCL2, BCL2L1 isoform Bcl-X(L),MCL1, BCL2A1 and BCL2L2. Interacts with BAX and BAK. Subcellular Location: Mitochondrion. Tissue Specificity: Ubiquitously expressed. SWISS: Q7L3V2 Gene ID: 79680 Database links: Entrez Gene: 79680 Human SwissProt: Q7L3V2 Human Unigene: 105642 Human |
| 产品图片 |
Sample:293T Cell (Human)Lysate at 40 ug
Primary: Anti-FBXL3(bs-15135R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 39kD
Observed band size: 45kD
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
