产品编号 | bs-15540R |
英文名称 | IDI2 Rabbit pAb |
中文名称 | 异戊烯基焦磷酸异构酶2抗体 |
别 名 | IDI2_HUMAN; Isopentenyl-diphosphate delta-isomerase 2; Isopentenyl pyrophosphate isomerase 2; IPP isomerase 2; IPPI2. |
研究领域 | 肿瘤 心血管 细胞生物 免疫学 信号转导 新陈代谢 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Mouse, (predicted: Human, Chicken, ) |
产品应用 | WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 27 kDa |
检测分子量 | |
细胞定位 | 细胞浆 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human IDI2: 1-100/227 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
IDI2 is a 227 amino acid protein that belongs to the IPP isomerase type 1 family. Localizing to the peroxisome, IDI2 is expressed in skeletal muscle and contains one nudix hydrolase domain. IDI2 utilizes magnesium as a cofactor and participates in isoprenoid biosythesis. IDI2 catalytically converts isopentenyl diphosphate (IPP) to its electrophilic isomer, dimethylallyl diphosphate (DMAPP), a substrate for subsequent reactions that synthesize farnesyl diphosphate and, ultimately, cholesterol. The gene encoding IDI2 maps to human chromosome 10p15.3. Segmental copy-number gains to the IDI2 gene may contribute to the pathogenesis of sporadic amyotrophic lateral sclerosis (SALS). SALS, also known as Lou Gehrig's disease, is a motor neuron disease characterized by neuron degeneration Function: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). Subcellular Location: Peroxisome. Tissue Specificity: Detected in skeletal muscle. Similarity: Belongs to the IPP isomerase type 1 family. Contains 1 nudix hydrolase domain. SWISS: Q9BXS1 Gene ID: 91734 Database links: Entrez Gene: 91734 Human Entrez Gene: 320581 Mouse SwissProt: Q9BXS1 Human SwissProt: Q4FZF0 Mouse Unigene: 591325 Human Unigene: 9270 Human |
产品图片 | |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |