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RabbitAnti-IDI2 Rabbit pAb  antibody (bs-15540R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-15540R
英文名称 IDI2 Rabbit pAb
中文名称 异戊烯基焦磷酸异构酶2抗体
别    名 IDI2_HUMAN; Isopentenyl-diphosphate delta-isomerase 2; Isopentenyl pyrophosphate isomerase 2; IPP isomerase 2; IPPI2.  
研究领域 肿瘤  心血管  细胞生物  免疫学  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Chicken, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 27 kDa
检测分子量
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IDI2: 1-100/227 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 IDI2 is a 227 amino acid protein that belongs to the IPP isomerase type 1 family. Localizing to the peroxisome, IDI2 is expressed in skeletal muscle and contains one nudix hydrolase domain. IDI2 utilizes magnesium as a cofactor and participates in isoprenoid biosythesis. IDI2 catalytically converts isopentenyl diphosphate (IPP) to its electrophilic isomer, dimethylallyl diphosphate (DMAPP), a substrate for subsequent reactions that synthesize farnesyl diphosphate and, ultimately, cholesterol. The gene encoding IDI2 maps to human chromosome 10p15.3. Segmental copy-number gains to the IDI2 gene may contribute to the pathogenesis of sporadic amyotrophic lateral sclerosis (SALS). SALS, also known as Lou Gehrig's disease, is a motor neuron disease characterized by neuron degeneration

Function:
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

Subcellular Location:
Peroxisome.

Tissue Specificity:
Detected in skeletal muscle.

Similarity:
Belongs to the IPP isomerase type 1 family.
Contains 1 nudix hydrolase domain.

SWISS:
Q9BXS1

Gene ID:
91734

Database links:

Entrez Gene: 91734 Human

Entrez Gene: 320581 Mouse

Entrez Gene: 502143 Rat

SwissProt: Q9BXS1 Human

SwissProt: Q4FZF0 Mouse

Unigene: 591325 Human

Unigene: 9270 Human



产品图片
Sample: Spleen (Mouse) Lysate at 40 ug Primary: Anti- IDI2 (bs-15540R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 27 kD Observed band size: 27 kD
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